TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human N-terminal His6-tagged PTP1B catalytic domain (1 to 393 residues) expressed in Escherichia coli strain Rosetta2 (DE3) using DiFMU...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human SHP1 (245 to 521 residues) expressed in Escherichia coli strain BL21(DE3) using DiFMUP as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human SHP2 (246 to 527 residues) expressed in Escherichia coli strain BL21(DE3) using DiFMUP as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human N-terminal His6-tagged PTP1B catalytic domain (1 to 298 residues) expressed in Escherichia coli strain Rosetta2 (DE3) using DiFMU...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN(Homo sapiens (Human))
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of human PTEN (1 to 403 residues) expressed in Escherichia coli strain BL21(DE3) using DiFMUP as substrate preincubated for 10 mins follow...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of human N-terminal His6-tagged TCPTP catalytic domain (1 to 336 residues) expressed in Escherichia coli strain Rosetta2 (DE3) using DiFMU...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human N-terminal His6-tagged TCPTP catalytic domain (1 to 296 residues) expressed in Escherichia coli strain Rosetta2 (DE3) using DiFMU...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase eta(Homo sapiens (Human))
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Affinity DataIC50: 1.12E+5nMAssay Description:Inhibition of human PTPRJ (1019 to 1311 residues) expressed in Escherichia coli strain BL21(DE3) using DiFMUP as substrate preincubated for 10 mins f...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Affinity DataIC50: 4.78E+5nMAssay Description:Inhibition of human N-terminal His6-tagged TCPTP catalytic domain (1 to 336 residues) expressed in Escherichia coli strain Rosetta2 (DE3) using DiFMU...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase epsilon(Homo sapiens (Human))
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human PTPRE (107 to 707 residues) expressed in Escherichia coli strain BL21(DE3) using DiFMUP as substrate preincubated for 10 mins fol...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Affinity DataIC50: 9.10E+5nMAssay Description:Inhibition of human N-terminal His6-tagged PTP1B catalytic domain (1 to 393 residues) expressed in Escherichia coli strain Rosetta2 (DE3) using DiFMU...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Affinity DataKoff: 59s-1Assay Description:Binding affinity to human N-terminal His6-tagged PTP1B catalytic domain (1 to 298 residues) expressed in Escherichia coli strain Rosetta2 (DE3) asses...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Affinity DataKd: 6.08E+3nMAssay Description:Binding affinity to human N-terminal His6-tagged PTP1B catalytic domain (1 to 298 residues) expressed in Escherichia coli strain Rosetta2 (DE3) by sw...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Helmholtz Zentrum M�Nchen
Curated by ChEMBL
Affinity DataKon: 0.000362M-1s-1Assay Description:Binding affinity to human N-terminal His6-tagged PTP1B catalytic domain (1 to 298 residues) expressed in Escherichia coli strain Rosetta2 (DE3) asses...More data for this Ligand-Target Pair