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Found 22 Enz. Inhib. hit(s) with all data for entry = 50007287
TargetHistone deacetylase 6(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50439674(RICOLINOSTAT | US10858323, Compound 2 | US11207431...)
Affinity DataIC50:  5nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  13nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 6(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508165(CHEMBL4592343)
Affinity DataIC50:  19nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508161(CHEMBL4579774)
Affinity DataIC50:  28nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508167(CHEMBL4469267)
Affinity DataIC50:  28nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  35nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50439674(RICOLINOSTAT | US10858323, Compound 2 | US11207431...)
Affinity DataIC50:  74nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508161(CHEMBL4579774)
Affinity DataIC50:  230nMAssay Description:Inhibition of FAM-Bid peptide binding to Bcl2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | US11420968, Example ABT-199 | Venetoclax)
Affinity DataIC50:  230nMAssay Description:Inhibition of FAM-Bid peptide binding to Bcl2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508167(CHEMBL4469267)
Affinity DataIC50:  240nMAssay Description:Inhibition of FAM-Bid peptide binding to Bcl2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508165(CHEMBL4592343)
Affinity DataIC50:  250nMAssay Description:Inhibition of FAM-Bid peptide binding to Bcl2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508165(CHEMBL4592343)
Affinity DataIC50:  281nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508167(CHEMBL4469267)
Affinity DataIC50:  665nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508161(CHEMBL4579774)
Affinity DataIC50:  847nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508162(CHEMBL4442030)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508164(CHEMBL4476315)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508166(CHEMBL4559296)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508163(CHEMBL4438858)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508166(CHEMBL4559296)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508163(CHEMBL4438858)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508164(CHEMBL4476315)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508162(CHEMBL4442030)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed