Found 50 Enz. Inhib. hit(s) with all data for entry = 50009557 Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of E2-activated human PDHK2More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of E2-activated human PDHK2More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human His-tagged PDK2 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
3D Structure (crystal)Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human His-tagged PDK2 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of E2-activated human PDHK2More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of E2-activated human PDHK2More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human His-tagged PDK1 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human His-tagged PDK1 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human His-tagged PDK3 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human His-tagged PDK3 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human His-tagged PDK4 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human His-tagged PDK4 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant human His-tagged PDK1 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant human His-tagged PDK1 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of human HSP90 measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of human HSP90 measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of recombinant human His-tagged PDK1 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of recombinant human His-tagged PDK1 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human His6-tagged N-terminal PDHK2 (A8 to T399 residues) expressed in baculovirus expression system using PDC as substrate ...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human His6-tagged N-terminal PDHK2 (A8 to T399 residues) expressed in baculovirus expression system using PDC as substrate ...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant human His-tagged PDK4 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant human His-tagged PDK4 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human HSP90 measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human HSP90 measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of human HSP90 measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of human HSP90 measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant human His-tagged PDK2 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant human His-tagged PDK2 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of recombinant human His-tagged PDK3 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of recombinant human His-tagged PDK3 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of recombinant human His-tagged PDK3 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of recombinant human His-tagged PDK3 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of recombinant human His-tagged PDK2 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of recombinant human His-tagged PDK2 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of recombinant human His-tagged PDK1 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of recombinant human His-tagged PDK1 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of recombinant human His-tagged PDK4 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of recombinant human His-tagged PDK4 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of recombinant human His-tagged PDK3 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of recombinant human His-tagged PDK3 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of recombinant human His-tagged PDK2 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of recombinant human His-tagged PDK2 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of recombinant human His-tagged PDK4 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of recombinant human His-tagged PDK4 expressed in Escherichia coli using PDH E1 as substrate measured after 30 mins by Kinase-Glo luminesc...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataKd: 870nMAssay Description:Binding affinity to recombinant human His-tagged PDK1 expressed in Escherichia coli by isothermal calorimetryMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataKd: 3.50E+3nMAssay Description:Binding affinity to recombinant human His-tagged PDK1 expressed in Escherichia coli by isothermal calorimetryMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataKd: 1.49E+3nMAssay Description:Binding affinity to recombinant human His-tagged PDK1 expressed in Escherichia coli by isothermal calorimetryMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataKd: 870nMAssay Description:Binding affinity to recombinant human His-tagged PDK1 expressed in Escherichia coli by isothermal calorimetryMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataKd: 1.49E+3nMAssay Description:Binding affinity to recombinant human His-tagged PDK1 expressed in Escherichia coli by isothermal calorimetryMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Jiangsu Normal University
Curated by ChEMBL
Jiangsu Normal University
Curated by ChEMBL
Affinity DataKd: 3.50E+3nMAssay Description:Binding affinity to recombinant human His-tagged PDK1 expressed in Escherichia coli by isothermal calorimetryMore data for this Ligand-Target Pair
