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Found 14 Enz. Inhib. hit(s) with all data for entry = 50009569
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  590nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  590nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli using arachidonic acid as substrate by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli using arachidonic acid as substrate by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50381224(CHEMBL2018554)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli using arachidonic acid as substrate by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50381224(CHEMBL2018554)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli using arachidonic acid as substrate by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50530006(CHEMBL4515606)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli using arachidonic acid as substrate by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50530006(CHEMBL4515606)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli using arachidonic acid as substrate by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50131688((E)-4-(3,5-dimethoxystyryl)phenol | 3,5-Dimethoxy-...)
Affinity DataIC50:  9.32E+3nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50131688((E)-4-(3,5-dimethoxystyryl)phenol | 3,5-Dimethoxy-...)
Affinity DataIC50:  9.32E+3nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50505498(CHEBI:31687 | Idebenone | Raxone)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50505498(CHEBI:31687 | Idebenone | Raxone)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50108046((oxyresveratrol)4-[(E)-2-(3,5-dihydroxyphenyl)viny...)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Vellore Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50108046((oxyresveratrol)4-[(E)-2-(3,5-dihydroxyphenyl)viny...)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed