Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with all data for entry = 50010280
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM25259(3-(decyloxy)-1-(2-hydrogen phosphonato-2-phosphono...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human FPPS using IPP and GPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM25271(3-[(3,7-dimethyloctyl)oxy]-1-(2-hydrogen phosphona...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human FPPS using IPP and GPP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM25271(3-[(3,7-dimethyloctyl)oxy]-1-(2-hydrogen phosphona...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human FPPS using IPP and GPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human FPPS using IPP and GPPMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM25259(3-(decyloxy)-1-(2-hydrogen phosphonato-2-phosphono...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM25263(bisphosphonate, 19 | {2-[3-(decyloxy)phenyl]-1-hyd...)
Affinity DataIC50:  590nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)(Escherichia coli (strain K12))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM25271(3-[(3,7-dimethyloctyl)oxy]-1-(2-hydrogen phosphona...)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of Escherichia coli UPPS in presence of IPP and FPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50537059(CHEMBL4543393)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human FPPS using IPP and GPP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM25263(bisphosphonate, 19 | {2-[3-(decyloxy)phenyl]-1-hyd...)
Affinity DataIC50:  5.50E+5nMAssay Description:Inhibition of human FPPS using IPP and GPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed