Found 39 Enz. Inhib. hit(s) with all data for entry = 50007524 TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of recombinant human wild-type N-terminal GST-His6-fused FGFR3 C-terminal domain (R397 to T806 residues) expressed in Sf9 insect cells usi...More data for this Ligand-Target Pair
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-His6-fused TRKB C-terminal domain (V526 to G838 residues) expressed in Sf9 insect cells using Poly(Glu...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-His6-fused SRPK1 (M1 to S655 residues) expressed in Sf9 insect cells using RS-peptide as s...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-His6-fused ERBB4 C-terminal domain (R676 to V1307 residues) expressed in Sf9 cells using Poly(Glu:Tyr)...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-His6-fused SRC (M1 to L536 residues) expressed in Sf9 insect cells using Poly(Glu:Tyr)4:1 ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human wild-type N-terminal GST-His6-fused EGFR C-terminal domain (H672 to A1210) expressed in Sf9 insect cells using Poly(G...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-His6-fused FGFR4 (R391 to T802 residues) expressed in baculovirus infected Sf9 cells using Poly(Glu:Ty...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-fused PDK1 (M1 to M460 residues) expressed in Sf9 insect cells using tetra(LRRWSLG) peptide as substr...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant human wild-type N-terminal GST-His6-fused KIT C-terminal domain (T544 to V976 residues) expressed in Sf9 insect cells using...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human wild-type N-terminal GST-His6-fused FGFR1 C-terminal domain (G400 to R820 residues) expressed in Sf9 insect cells usi...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-His6-fused CLK1 (M1 to I484 residues) expressed in Sf9 cells using RS-peptide as substrate...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of recombinant human wild-type N-terminal GST-His6-fused TRKA C-terminal domain (G443 to G796 residues) expressed in Sf9 insect cells usin...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant human MAP3K10 measured after 60 mins in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-His6-fused AKT2 C-terminal domain (A107 to E481 residues) expressed in Sf9 insect cells using GSK3(14-...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-His6-fused FGFR2 C-terminal domain (R400 to T822 residues) expressed in Sf9 insect cells using TRK-C d...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of recombinant human wild-type N-terminal GST-His6-fused ERBB2 C-terminal domain (Q679 to V1255 residues) expressed in Sf9 insect cells us...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-fused VEGFR2 C-terminal domain (D807 to V1356 residues) expressed in Sf9 insect cells using Poly(Glu:T...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of recombinant human ROCK1 measured after 60 mins in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged VEGFR1 C-terminal domain (K784 to I1338 residues) expressed in Sf9 insect cells using Poly(Glu:...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of recombinant human wild-type N-terminal GST-His6-fused PDGFR-alpha C-terminal domain (Q551 to L1089 residues) expressed in Sf9 insect ce...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of recombinant human wild-type N-terminal GST-His6-fused MET C-terminal domain (K956 to S1390 residues) expressed in Sf9 insect cells usin...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 15(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of recombinant human N-terminal 4xFLAG-tagged/C-terminal His8-fused ERK7 N-terminal domain (M1 to R354 residues) expressed in Sf9 insect c...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-His6 fused ERK1 (M1 to P379 residues) expressed in Escherichia coli using RBER-CHKtide as ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 1(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of recombinant human N-terminal 4xFLAG-tagged/C-terminal His8 fused MAP3K1 C-terminal domain (M1193 to W1512 residues) expressed in Sf9 in...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of recombinant human full-length untagged ERK2 (M1 to S360 residues) expressed in Escherichia coli using recombinant ELK1 as substrate mea...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibition of recombinant human wild-type N-terminal GST-His6-fused ABL1 internal domain (P118 to S535 residues) expressed in Sf9 insect cells using ...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of recombinant human MEK2 measured after 60 mins in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of recombinant human CHK2 measured after 60 mins in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-His6-fused WEE1 C-terminal domain (Q36 to Y432 residues) expressed in Sf9 cells using Poly(Ala,Glu,Lys...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-His6-fused PDGFR-beta C-terminal domain (R561 to L1106 residues) expressed in Sf9 insect cells using P...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 8.80E+4nMAssay Description:Inhibition of recombinant human full-length untagged p38-alpha (M1 to S360 residues) expressed in Escherichia coli cells using recombinant ATF2 as su...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged/C-terminal His8 fused ERK5 internal fragment domain (L5 to Q397 residues) expressed in Sf9 ins...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha'(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 9.90E+4nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-His6-fused CK2-alpha2 (M1 to R350 residues) expressed in Sf9 insect cells using casein as ...More data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-fused FAK (2 to 1052 residues) expressed in Sf9 insect cells using Poly(Glu/Tyr)4:1 as substrate measu...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-His6 fused VEGFR3 C-terminal domain (N799 to R1298 residues) expressed in baculovirus infected Sf9 ins...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MAP3K9 measured after 60 mins in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human wild-type full-length MEK1 (M1 to V393 residues) expressed in Sf9 insect cells using ERK2-K54R as substrate measured ...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-His6-fused AKT2 (M1 to E481 residues) expressed in Sf9 insect cells using GSK3-derived pep...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused CK2-alpha1 (M1 to Q391 residues) expressed in Sf9 insect cells using casein as subst...More data for this Ligand-Target Pair
