Found 23 Enz. Inhib. hit(s) with all data for entry = 50006975 TargetMacrophage metalloelastase(Homo sapiens (Human))
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Inhibition of human MMP12More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Inhibition of human MMP12More data for this Ligand-Target Pair
3D Structure (crystal)Target72 kDa type IV collagenase(Homo sapiens (Human))
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of human MMP2 by photoaffinity probe based assayMore data for this Ligand-Target Pair
TargetNeutrophil collagenase(Homo sapiens (Human))
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Inhibition of human MMP8 by photoaffinity probe based assayMore data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Inhibition of human MMP12More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of human MMP12 by photoaffinity probe based assayMore data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of human MMP13 by photoaffinity probe based assayMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Inhibition of human MMP9 by photoaffinity probe based assayMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 4.60nMAssay Description:Inhibition of human recombinant LTA4H by L-(4-benzoyl)phenylalanyl-beta-naphthylamide fluorigenic substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 5.30nMAssay Description:Inhibition of human recombinant LTA4H by L-(4-benzoyl)phenylalanyl-beta-naphthylamide fluorigenic substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetM17 leucyl aminopeptidase(Plasmodium falciparum 3D7)
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of Plasmodium falciparum LAPMore data for this Ligand-Target Pair
TargetM17 leucyl aminopeptidase(Plasmodium falciparum 3D7)
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of Plasmodium falciparum LAPMore data for this Ligand-Target Pair
TargetAminopeptidase N(Sus scrofa (Pig))
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:Inhibition of porcine APNMore data for this Ligand-Target Pair
TargetCytosol aminopeptidase(Sus scrofa)
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 66nMAssay Description:Inhibition of porcine LAPMore data for this Ligand-Target Pair
TargetCytosol aminopeptidase(Sus scrofa)
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 67nMAssay Description:Inhibition of porcine LAPMore data for this Ligand-Target Pair
TargetAminopeptidase N(Sus scrofa (Pig))
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 276nMAssay Description:Inhibition of porcine APNMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human IRAP using L-leucine 7-amido-4-methyl coumarin substrate by microplate fluorescence reader based assayMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human IRAP using L-leucine 7-amido-4-methyl coumarin substrate by microplate fluorescence reader based assayMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human IRAP using L-leucine 7-amido-4-methyl coumarin substrate by microplate fluorescence reader based assayMore data for this Ligand-Target Pair
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of ERAP2 (unknown origin)More data for this Ligand-Target Pair
TargetEndoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of ERAP1 (unknown origin)More data for this Ligand-Target Pair
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Inhibition of ERAP2 (unknown origin)More data for this Ligand-Target Pair
TargetEndoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Wroc?Aw University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of ERAP1 (unknown origin)More data for this Ligand-Target Pair
