Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50008897
TargetAromatase(Human)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM50135997(CHEMBL3754471)
Affinity DataKi:  23nMAssay Description:Competitive irreversible inhibition of human placental microsome aromatase using varying levels of [1beta3H]-androstenedione as substrate measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM50135997(CHEMBL3754471)
Affinity DataKi:  25nMAssay Description:Competitive reversible inhibition of human placental microsome aromatase using varying levels of [1beta3H]-androstenedione as substrate measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM50398447(Aromasin | EXEMESTANE)
Affinity DataKi:  26nMAssay Description:Competitive inhibition of human placental microsome aromatase using varying levels of [1beta2beta3H]-androstenedione as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAromatase(Human)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM50523404(CHEMBL4575994)
Affinity DataIC50: 55nMAssay Description:Inhibition of human placental microsome aromatase using [1beta3H]-androstenedione as substrate measured after 15 mins in presence of NADPH by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM50135997(CHEMBL3754471)
Affinity DataIC50: 60nMAssay Description:Inhibition of human placental microsome aromatase using [1beta3H]-androstenedione as substrate measured after 15 mins in presence of NADPH by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM50523395(CHEMBL4514728)
Affinity DataIC50: 105nMAssay Description:Inhibition of human placental microsome aromatase using [1beta3H]-androstenedione as substrate measured after 15 mins in presence of NADPH by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM50523399(CHEMBL4454575)
Affinity DataIC50: 110nMAssay Description:Inhibition of human placental microsome aromatase using [1beta3H]-androstenedione as substrate measured after 15 mins in presence of NADPH by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM50135862(CHEMBL3751881)
Affinity DataIC50: 170nMAssay Description:Inhibition of human placental microsome aromatase using [1beta3H]-androstenedione as substrate measured after 15 mins in presence of NADPH by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM50523403(CHEMBL4460869)
Affinity DataIC50: 175nMAssay Description:Inhibition of human placental microsome aromatase using [1beta3H]-androstenedione as substrate measured after 15 mins in presence of NADPH by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM50523400(CHEMBL4520056)
Affinity DataIC50: 210nMAssay Description:Inhibition of human placental microsome aromatase using [1beta3H]-androstenedione as substrate measured after 15 mins in presence of NADPH by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM50523396(CHEMBL487113)
Affinity DataIC50: 270nMAssay Description:Inhibition of human placental microsome aromatase using [1beta3H]-androstenedione as substrate measured after 15 mins in presence of NADPH by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM50523397(CHEMBL4451962)
Affinity DataIC50: 405nMAssay Description:Inhibition of human placental microsome aromatase using [1beta3H]-androstenedione as substrate measured after 15 mins in presence of NADPH by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM50523402(CHEMBL4468497)
Affinity DataIC50: 520nMAssay Description:Inhibition of human placental microsome aromatase using [1beta3H]-androstenedione as substrate measured after 15 mins in presence of NADPH by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM50523398(CHEMBL4564333)
Affinity DataIC50: 560nMAssay Description:Inhibition of human placental microsome aromatase using [1beta3H]-androstenedione as substrate measured after 15 mins in presence of NADPH by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM50523401(CHEMBL4515880)
Affinity DataIC50: 840nMAssay Description:Inhibition of human placental microsome aromatase using [1beta3H]-androstenedione as substrate measured after 15 mins in presence of NADPH by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
University of Coimbra

Curated by ChEMBL
LigandPNGBDBM50523405(CHEMBL4520027)
Affinity DataIC50: 880nMAssay Description:Inhibition of human placental microsome aromatase using [1beta3H]-androstenedione as substrate measured after 15 mins in presence of NADPH by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed