BindingDB PrimarySearch_ki

Found 95 Enz. Inhib. hit(s) with all data for entry = 50010326

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)

IC50: 0.5nMAssay Description:Inhibition of human JAK2 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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CHEMBL DrugBank MCE
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3D Structure (crystal)

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)

IC50: 0.700nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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CHEMBL DrugBank MCE
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Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537422(CHEMBL4584430)

IC50: 1nMAssay Description:Inhibition of human GST-tagged JAK3 using FITC-KGGEEEEYFELVKK as substrate by fluorescence assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)

IC50: 1.40nMAssay Description:Inhibition of human JAK1 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50109518(CHEMBL3601722)

IC50: 2.10nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537427(CHEMBL4573218)

IC50: 2.40nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537444(CHEMBL4546009)

IC50: 3.5nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537417(CHEMBL4518786)

IC50: 4.80nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537441(CHEMBL4574614)

IC50: 7nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537415(CHEMBL4572373)

IC50: 7.20nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537433(CHEMBL4563864)

IC50: 7.30nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537442(CHEMBL4577029)

IC50: 7.90nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537421(CHEMBL4566849)

IC50: 8.40nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537426(CHEMBL4593058)

IC50: 9.30nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537436(CHEMBL4541547)

IC50: 9.40nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537425(CHEMBL4539137)

IC50: 12nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537418(CHEMBL4526018)

IC50: 24nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)

IC50: 32nMAssay Description:Inhibition of human TYK2 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank
PDB

3D Structure (crystal)

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM209866(PF-06651600 | US11111242, Example 5 | US2023034848...)

IC50: 33nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase PC cid PC sid

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537419(CHEMBL4566777)

IC50: 89nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537428(CHEMBL4581532)

IC50: 90nMAssay Description:Inhibition of human JAK1 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537432(CHEMBL4516549)

IC50: 92nMAssay Description:Inhibition of human JAK1 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537439(CHEMBL4560222)

IC50: 99nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537429(CHEMBL4588496)

IC50: 101nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537430(CHEMBL4524497)

IC50: 124nMAssay Description:Inhibition of human JAK1 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537438(CHEMBL4555932)

IC50: 155nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537416(CHEMBL4537782)

IC50: 212nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537431(CHEMBL4528217)

IC50: 278nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537437(CHEMBL4589415)

IC50: 280nMAssay Description:Inhibition of human JAK2 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537434(CHEMBL4525246)

IC50: 285nMAssay Description:Inhibition of human JAK1 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537443(CHEMBL4521305)

IC50: 290nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537435(CHEMBL4552985)

IC50: 342nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537432(CHEMBL4516549)

IC50: 345nMAssay Description:Inhibition of human JAK2 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537428(CHEMBL4581532)

IC50: 350nMAssay Description:Inhibition of human JAK2 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537440(CHEMBL4591192)

IC50: 366nMAssay Description:Inhibition of human JAK2 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537420(CHEMBL4571470)

IC50: 389nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537430(CHEMBL4524497)

IC50: 503nMAssay Description:Inhibition of human JAK2 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537424(CHEMBL4556768)

IC50: 589nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537418(CHEMBL4526018)

IC50: 643nMAssay Description:Inhibition of human JAK1 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537425(CHEMBL4539137)

IC50: 656nMAssay Description:Inhibition of human JAK1 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537423(CHEMBL4587735)

IC50: 730nMAssay Description:Inhibition of human JAK3 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537442(CHEMBL4577029)

IC50: 731nMAssay Description:Inhibition of human JAK1 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537441(CHEMBL4574614)

IC50: 774nMAssay Description:Inhibition of human JAK1 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537426(CHEMBL4593058)

IC50: 852nMAssay Description:Inhibition of human JAK1 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537421(CHEMBL4566849)

IC50: 916nMAssay Description:Inhibition of human JAK2 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537417(CHEMBL4518786)

IC50: 920nMAssay Description:Inhibition of human JAK1 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537444(CHEMBL4546009)

IC50: 923nMAssay Description:Inhibition of human JAK1 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50109518(CHEMBL3601722)

IC50: 945nMAssay Description:Inhibition of human JAK2 using TK-substrate-biotin preincubated for 5 mins followed by substrate addition and further incubated for 30 mins and subse...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537422(CHEMBL4584430)

IC50: >1.00E+3nMAssay Description:Inhibition of human GST-tagged JAK2 by fluorescence assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50537422(CHEMBL4584430)

IC50: >1.00E+3nMAssay Description:Inhibition of human GST-tagged JAK1 by fluorescence assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

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