Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50007714
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of HER4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50:  3nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512005(CHEMBL4440181)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50:  10nMAssay Description:Inhibition of BLK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant LYN using biotinyl-beta amyloid beta amyloid beta AKVEKIGEGTYGVVYK as substrate measured after 120 mins in the presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD measured after 15 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant JAK3 using Ulight-CAGAGAIETDKEYYTVKD measured after 60 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant HER2 using biotinyl-beta amyloid beta amyloid beta AAEEEEYFELVAKKK measured after 10 mins in the presence of ATP by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50:  28nMAssay Description:Inhibition of human recombinant FGR using Ulight-TK peptide as substrate measured after 60 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50:  31nMAssay Description:Inhibition of human recombinant LCK using Ulight-Poly GAT[EAY(1:1:1) as substrate measured after 10 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512009(CHEMBL4544821)
Affinity DataIC50:  31nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50:  33nMAssay Description:Inhibition of HCK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512002(CHEMBL4443198)
Affinity DataIC50:  37nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512003(CHEMBL4571839)
Affinity DataIC50:  42nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50:  44nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512000(CHEMBL4582791)
Affinity DataIC50:  45nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512007(CHEMBL4455094)
Affinity DataIC50:  46nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50:  83nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50:  86nMAssay Description:Inhibition of human recombinant YES using biotinyl-beta amyloid beta amyloid beta AYQAEENTYDEYEN as substrate measured after 30 mins in the presence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512004(CHEMBL4561220)
Affinity DataIC50:  89nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512006(CHEMBL4457802)
Affinity DataIC50:  123nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50:  123nMAssay Description:Inhibition of human recombinant SRC using Ulight-Poly GAT[EAY(1:1:1) as substrate measured after 10 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50:  232nMAssay Description:Inhibition of human recombinant FYN using biotinyl-beta amyloid beta amyloid beta AYQAEENTYDEYEN as substrate measured after 60 mins in the presence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50:  358nMAssay Description:Inhibition of human recombinant TXK using Ulight-Poly GAT[EAY(1:1:1) as substrate measured after 30 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50:  385nMAssay Description:Inhibition of HER4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512001(CHEMBL4535899)
Affinity DataIC50: >500nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511998(CHEMBL4514557)
Affinity DataIC50: >500nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512008(CHEMBL4588815)
Affinity DataIC50: >500nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511999(CHEMBL4472161)
Affinity DataIC50: >500nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant ITK using Ulight-TK peptide as substrate measured after 30 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD measured after 15 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant HER2 using biotinyl-beta amyloid beta amyloid beta AAEEEEYFELVAKKK measured after 10 mins in the presence of ATP by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant JAK3 using Ulight-CAGAGAIETDKEYYTVKD measured after 60 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed