Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with all data for entry = 50007727
TargetCytochrome P450 3A4(Homo sapiens (Human))
Beijing Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)
Affinity DataIC50:  60nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 10 mins after substrate addition by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Beijing Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50512134(CHEMBL4474918)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 10 mins after substrate addition by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Beijing Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50378137(Ketek | TELITHROMYCIN)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 10 mins after substrate addition by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed