Found 26 Enz. Inhib. hit(s) with all data for entry = 50008983 TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 3.80E+3nMAssay Description:Inhibition of BCRP (unknown origin) in MDCK-MDR1 assessed as inhibtion of hoechst 33342 transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 3.90E+3nMAssay Description:Inhibition of BCRP (unknown origin) in MDCK-MDR1 assessed as inhibtion of hoechst 33342 transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Inhibition of MRP1 (unknown origin) in MDCK-MDR1 assessed as inhibtion of calcein-AM transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 520nMAssay Description:Inhibition of P-glycoprotein (unknown origin) in MDCK-MDR1 assessed as inhibtion of calcein-AM transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 850nMAssay Description:Inhibition of P-glycoprotein (unknown origin) in MDCK-MDR1 assessed as inhibtion of calcein-AM transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 260nMAssay Description:Inhibition of P-glycoprotein (unknown origin) in MDCK-MDR1 assessed as inhibtion of calcein-AM transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 220nMAssay Description:Inhibition of P-glycoprotein (unknown origin) in MDCK-MDR1 assessed as inhibtion of calcein-AM transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 340nMAssay Description:Inhibition of P-glycoprotein (unknown origin) in MDCK-MDR1 assessed as inhibtion of calcein-AM transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 5.08E+3nMAssay Description:Inhibition of MRP1 (unknown origin) in MDCK-MDR1 assessed as inhibtion of calcein-AM transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 4.50E+3nMAssay Description:Inhibition of MRP1 (unknown origin) in MDCK-MDR1 assessed as inhibtion of calcein-AM transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 6.80E+3nMAssay Description:Inhibition of MRP1 (unknown origin) in MDCK-MDR1 assessed as inhibtion of calcein-AM transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 1.60E+4nMAssay Description:Inhibition of BCRP (unknown origin) in MDCK-MDR1 assessed as inhibtion of hoechst 33342 transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 3.30E+3nMAssay Description:Inhibition of BCRP (unknown origin) in MDCK-MDR1 assessed as inhibtion of hoechst 33342 transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Inhibition of BCRP (unknown origin) in MDCK-MDR1 assessed as inhibtion of hoechst 33342 transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 4.50E+3nMAssay Description:Inhibition of BCRP (unknown origin) in MDCK-MDR1 assessed as inhibtion of hoechst 33342 transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 5.10E+3nMAssay Description:Inhibition of BCRP (unknown origin) in MDCK-MDR1 assessed as inhibtion of hoechst 33342 transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Inhibition of P-glycoprotein (unknown origin) in MDCK-MDR1 assessed as inhibtion of calcein-AM transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Inhibition of P-glycoprotein (unknown origin) in MDCK-MDR1 assessed as inhibtion of calcein-AM transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 230nMAssay Description:Inhibition of P-glycoprotein (unknown origin) in MDCK-MDR1 assessed as inhibtion of calcein-AM transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 500nMAssay Description:Inhibition of P-glycoprotein (unknown origin) in MDCK-MDR1 assessed as inhibtion of calcein-AM transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 2.20E+3nMAssay Description:Inhibition of MRP1 (unknown origin) in MDCK-MDR1 assessed as inhibtion of calcein-AM transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 8.10E+3nMAssay Description:Inhibition of BCRP (unknown origin) in MDCK-MDR1 assessed as inhibtion of hoechst 33342 transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 5.40E+3nMAssay Description:Inhibition of BCRP (unknown origin) in MDCK-MDR1 assessed as inhibtion of hoechst 33342 transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 920nMAssay Description:Inhibition of P-glycoprotein (unknown origin) in MDCK-MDR1 assessed as inhibtion of calcein-AM transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 3.80E+3nMAssay Description:Inhibition of BCRP (unknown origin) in MDCK-MDR1 assessed as inhibtion of hoechst 33342 transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 210nMAssay Description:Inhibition of P-glycoprotein (unknown origin) in MDCK-MDR1 assessed as inhibtion of calcein-AM transport incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
