Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50008924
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523667(CHEMBL4560054)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523668(CHEMBL4550603)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)
Affinity DataIC50:  5nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523669(CHEMBL4535169)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)
Affinity DataIC50:  6nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523672(CHEMBL4440218)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)
Affinity DataIC50:  8nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523664(CHEMBL4454741)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523673(CHEMBL4589873)
Affinity DataIC50:  11nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523670(CHEMBL4467333)
Affinity DataIC50:  11nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)
Affinity DataIC50:  14nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523674(CHEMBL4536349)
Affinity DataIC50:  18nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523665(CHEMBL4542493)
Affinity DataIC50:  20nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523666(CHEMBL4462149)
Affinity DataIC50:  28nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523671(CHEMBL4563971)
Affinity DataIC50:  29nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523664(CHEMBL4454741)
Affinity DataIC50:  38nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523668(CHEMBL4550603)
Affinity DataIC50:  42nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)
Affinity DataIC50:  79nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)
Affinity DataIC50:  92nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523667(CHEMBL4560054)
Affinity DataIC50:  112nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523668(CHEMBL4550603)
Affinity DataIC50:  241nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523668(CHEMBL4550603)
Affinity DataIC50:  289nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523664(CHEMBL4454741)
Affinity DataIC50:  342nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523664(CHEMBL4454741)
Affinity DataIC50:  421nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)
Affinity DataIC50:  571nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523668(CHEMBL4550603)
Affinity DataIC50:  580nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523667(CHEMBL4560054)
Affinity DataIC50:  589nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523664(CHEMBL4454741)
Affinity DataIC50:  676nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)
Affinity DataIC50:  831nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523667(CHEMBL4560054)
Affinity DataIC50:  891nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523667(CHEMBL4560054)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523667(CHEMBL4560054)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed