Found 10 Enz. Inhib. hit(s) with all data for entry = 50004195 
Affinity DataIC50: 530nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincuba...More data for this Ligand-Target Pair
TargetLymphocyte antigen 96/Toll-like receptor 4(Mus musculus)
Wenzhou Medical University
Curated by ChEMBL
Wenzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincuba...More data for this Ligand-Target Pair
Affinity DataIC50: 840nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincuba...More data for this Ligand-Target Pair
Affinity DataIC50: 890nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production prein...More data for this Ligand-Target Pair
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production prein...More data for this Ligand-Target Pair
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincuba...More data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production prein...More data for this Ligand-Target Pair
Affinity DataIC50: 6.99E+3nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production prein...More data for this Ligand-Target Pair
Affinity DataKd: 1.85E+5nMAssay Description:Binding affinity to recombinant human 10His-tagged MD2 (Glu17 to Asn160 residues) expressed in Escherichia coli by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.46E+5nMAssay Description:Binding affinity to recombinant human C-terminal 10His-tagged TLR4 (Glu24 to Lys631 residues) expressed in mouse NS0 cells by surface plasmon resonan...More data for this Ligand-Target Pair
