Found 60 Enz. Inhib. hit(s) with all data for entry = 50008996 TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant human H3 receptor expressed in HEK293T cells measured after 90 mins by liquid scintillat...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataKi: 6.10nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant human H3 receptor expressed in HEK293T cells measured after 90 mins by liquid scintillat...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: <50nMAssay Description:Displacement of [I125]bolton hunter-CCK-8S from recombinant human CCK1 receptor expressed in stable CHO cells measured after 1 to 2 hrs by microscint...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 245nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: <300nMAssay Description:Inhibition of tracer Red binding to human ERG expressed in membranes after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 912nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 1.29E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 2.69E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 2.71E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 2.75E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 2.75E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 2.93E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 2.95E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 3.09E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 4.45E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 4.47E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 4.57E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 4.61E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 4.68E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 4.68E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 5.50E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 5.50E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 6.76E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 6.80E+3nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 1.23E+4nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataIC50: 1.23E+4nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataEC50: 95nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataEC50: 1.29E+3nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataEC50: 1.39E+3nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataEC50: 78nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataEC50: 5.25E+3nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataEC50: 2.12E+3nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataEC50: 360nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataEC50: 891nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataEC50: 5.37E+3nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataEC50: 880nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataEC50: 250nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Academy Of Scientific And Innovative Research (Acsir)
Curated by ChEMBL
Affinity DataEC50: 840nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
