TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of P-gp in HEK293/ABCB1 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin IC50 at 1 uM incubated...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of P-gp in human NCI-H460/R cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring reduction in doxorubicin IC50 ...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 920nMAssay Description:Inhibition of P-gp in HEK293/ABCB1 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin IC50 at 2 uM incubated for...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of P-gp-mediated Rhodamine-123 efflux in human MCF-7/DOX cells assessed as Rhodamine-123 accumulation preincubated for 15 mins followed by...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of P-gp in human Caco2 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring reduction in doxorubicin IC50 at 2....More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 1.25E+7nMAssay Description:Inhibition of P-gp in human HK2 cells assessed as Rhodamine-123 accumulation by fluorescence assayMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 2.49E+7nMAssay Description:Inhibition of P-gp in human HK2 cells assessed as Rhodamine-123 accumulation by fluorescence assayMore data for this Ligand-Target Pair