Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50002455
LigandChemical structure of BindingDB Monomer ID 16312BDBM16312(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
Affinity DataIC50: 73nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50016550BDBM50016550(CHEMBL37092 | (4-Benzoylamino-benzenesulfonylamino...)
Affinity DataIC50: 410nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022333BDBM50022333([4-(3-Phenyl-acryloylamino)-benzenesulfonylamino]-...)
Affinity DataIC50: 690nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022337BDBM50022337((4-Phenylacetylamino-benzenesulfonylamino)-acetic ...)
Affinity DataIC50: 2.17E+3nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022338BDBM50022338([4-(2-Phenoxy-acetylamino)-benzenesulfonylamino]-a...)
Affinity DataIC50: 2.64E+3nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022334BDBM50022334([4-(3-Phenyl-ureido)-benzenesulfonylamino]-acetic ...)
Affinity DataIC50: 2.75E+3nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022342BDBM50022342([4-(2-Benzyloxy-acetylamino)-benzenesulfonylamino]...)
Affinity DataIC50: 3.50E+3nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022345BDBM50022345((4-Acetylamino-benzenesulfonylamino)-acetic acid |...)
Affinity DataIC50: 4.22E+3nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022336BDBM50022336((4-Benzyloxycarbonylamino-benzenesulfonylamino)-ac...)
Affinity DataIC50: 6.03E+3nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022339BDBM50022339((4-Benzylamino-benzenesulfonylamino)-acetic acid |...)
Affinity DataIC50: 7.04E+3nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022343BDBM50022343((3-Benzoylamino-benzenesulfonylamino)-acetic acid ...)
Affinity DataIC50: 7.12E+3nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022340BDBM50022340([4-(3-Phenyl-thioureido)-benzenesulfonylamino]-ace...)
Affinity DataIC50: 8.42E+3nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022344BDBM50022344((4-Dimethylamino-benzenesulfonylamino)-acetic acid...)
Affinity DataIC50: 1.09E+4nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022335BDBM50022335([4-(3-Phenyl-propionylamino)-benzenesulfonylamino]...)
Affinity DataIC50: 1.15E+4nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50016581BDBM50016581(CHEMBL285053 | (4-Amino-benzenesulfonylamino)-acet...)
Affinity DataIC50: 1.60E+4nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50016541BDBM50016541(CHEMBL289897 | (3-Amino-benzenesulfonylamino)-acet...)
Affinity DataIC50: 2.90E+4nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50016562BDBM50016562(CHEMBL38109 | (2-Amino-benzenesulfonylamino)-aceti...)
Affinity DataIC50: 3.80E+4nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022341BDBM50022341((2-Benzoylamino-benzenesulfonylamino)-acetic acid ...)
Affinity DataIC50: 7.80E+4nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed