Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50002455
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  73nMAssay Description:Concentration required to produce 50% inhibition of aldose reductase enzyme (the literature IC50 value for sorbinil is 0.07 uM)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016550((4-Benzoylamino-benzenesulfonylamino)-acetic acid ...)
Affinity DataIC50:  410nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022333(CHEMBL41232 | [4-(3-Phenyl-acryloylamino)-benzenes...)
Affinity DataIC50:  690nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022337((4-Phenylacetylamino-benzenesulfonylamino)-acetic ...)
Affinity DataIC50:  2.17E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022338(CHEMBL417523 | [4-(2-Phenoxy-acetylamino)-benzenes...)
Affinity DataIC50:  2.64E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022334(CHEMBL40666 | [4-(3-Phenyl-ureido)-benzenesulfonyl...)
Affinity DataIC50:  2.75E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022342(CHEMBL40681 | [4-(2-Benzyloxy-acetylamino)-benzene...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022345((4-Acetylamino-benzenesulfonylamino)-acetic acid |...)
Affinity DataIC50:  4.22E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022336((4-Benzyloxycarbonylamino-benzenesulfonylamino)-ac...)
Affinity DataIC50:  6.03E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022339((4-Benzylamino-benzenesulfonylamino)-acetic acid |...)
Affinity DataIC50:  7.04E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022343((3-Benzoylamino-benzenesulfonylamino)-acetic acid ...)
Affinity DataIC50:  7.12E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022340(CHEMBL39090 | [4-(3-Phenyl-thioureido)-benzenesulf...)
Affinity DataIC50:  8.42E+3nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022344((4-Dimethylamino-benzenesulfonylamino)-acetic acid...)
Affinity DataIC50:  1.09E+4nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022335(CHEMBL40492 | [4-(3-Phenyl-propionylamino)-benzene...)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016581((4-Amino-benzenesulfonylamino)-acetic acid | 2-(4-...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016541((3-Amino-benzenesulfonylamino)-acetic acid | CHEMB...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50016562((2-Amino-benzenesulfonylamino)-acetic acid | CHEMB...)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022341((2-Benzoylamino-benzenesulfonylamino)-acetic acid ...)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibition of rat aldose reductase enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed