Compile Data Set for Download or QSAR
maximum 50k data
Found 50 Enz. Inhib. hit(s) with all data for entry = 50008027
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM109086(US10793535, Cmpd ID 727 | US8604016, 670 | US99382...)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514979(CHEMBL4457936)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514986(CHEMBL4437956)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514985(CHEMBL4573635)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514975(CHEMBL4473143)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50150109(CHEMBL3770355)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514977(CHEMBL4461749)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514982(CHEMBL4469711)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM278400((2S)-2-Methoxy-2-phenyl-N-[5-[[(3R)-1-pyridazin-3-...)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514978(CHEMBL4451434)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM278400((2S)-2-Methoxy-2-phenyl-N-[5-[[(3R)-1-pyridazin-3-...)
Affinity DataIC50:  51nMAssay Description:Inhibition of GLS1 GAC isoform (unknown origin) using glutamine as substrate preincubated for 15 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM108464(US8604016, 21 | US9938267, Cmpd ID 21)
Affinity DataIC50:  51nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50172138(CHEMBL3808443 | US10040788, Example 1(a) | US10294...)
Affinity DataIC50:  63nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514990(CHEMBL4448931)
Affinity DataIC50:  65nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514974(CHEMBL4472367)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514989(CHEMBL4444363)
Affinity DataIC50:  99nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514991(CHEMBL4594003)
Affinity DataIC50:  114nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50400050(CHEMBL2177757 | US10793535, Cmpd ID 1 | US11191732...)
Affinity DataIC50:  135nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM108512(US8604016, 72 | US9938267, Cmpd ID 72)
Affinity DataIC50:  202nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514983(CHEMBL4447951)
Affinity DataIC50:  207nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514988(CHEMBL4548654)
Affinity DataIC50:  244nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514980(CHEMBL4438255)
Affinity DataIC50:  347nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM108454(US8604016, 11 | US9938267, Cmpd ID 11)
Affinity DataIC50:  380nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514984(CHEMBL4534437)
Affinity DataIC50:  590nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514987(CHEMBL4570299)
Affinity DataIC50:  873nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514976(CHEMBL4458193)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM278400((2S)-2-Methoxy-2-phenyl-N-[5-[[(3R)-1-pyridazin-3-...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514981(CHEMBL4434859)
Affinity DataIC50:  6.05E+3nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM278400((2S)-2-Methoxy-2-phenyl-N-[5-[[(3R)-1-pyridazin-3-...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of 5HT2B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50172138(CHEMBL3808443 | US10040788, Example 1(a) | US10294...)
Affinity DataIC50: >3.33E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM278400((2S)-2-Methoxy-2-phenyl-N-[5-[[(3R)-1-pyridazin-3-...)
Affinity DataIC50: >3.33E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514976(CHEMBL4458193)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM108512(US8604016, 72 | US9938267, Cmpd ID 72)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514983(CHEMBL4447951)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514982(CHEMBL4469711)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514987(CHEMBL4570299)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514980(CHEMBL4438255)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514975(CHEMBL4473143)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50150109(CHEMBL3770355)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514986(CHEMBL4437956)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514977(CHEMBL4461749)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50400050(CHEMBL2177757 | US10793535, Cmpd ID 1 | US11191732...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514990(CHEMBL4448931)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM108464(US8604016, 21 | US9938267, Cmpd ID 21)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514974(CHEMBL4472367)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514989(CHEMBL4444363)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514978(CHEMBL4451434)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM278400((2S)-2-Methoxy-2-phenyl-N-[5-[[(3R)-1-pyridazin-3-...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of OPRM (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM278400((2S)-2-Methoxy-2-phenyl-N-[5-[[(3R)-1-pyridazin-3-...)
Affinity DataIC50:  6.10E+4nMAssay Description:Inhibition of dopamine transporter (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM278400((2S)-2-Methoxy-2-phenyl-N-[5-[[(3R)-1-pyridazin-3-...)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibition of NK1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed