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Found 6 Enz. Inhib. hit(s) with all data for entry = 50010148
TargetSerine/threonine-protein kinase mTOR(Mus musculus (Mouse))
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM36609(Rapamycin C-7, analog 4 | SIROLIMUS | US11603377, ...)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of mTOR in mouse TSC1-/- MEF cells assessed as inhibition of S6 Ser240/244 phosphorylation incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Mus musculus (Mouse))
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50535638(CHEMBL4529771)
Affinity DataIC50:  0.170nMAssay Description:Inhibition of mTOR in mouse TSC1-/- MEF cells assessed as inhibition of S6 Ser240/244 phosphorylation incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Mus musculus (Mouse))
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50535641(CHEMBL4591064)
Affinity DataIC50:  0.274nMAssay Description:Inhibition of mTOR in mouse TSC1-/- MEF cells assessed as inhibition of S6 Ser240/244 phosphorylation incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Mus musculus (Mouse))
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50535642(CHEMBL4465976)
Affinity DataIC50:  0.374nMAssay Description:Inhibition of mTOR in mouse TSC1-/- MEF cells assessed as inhibition of S6 Ser240/244 phosphorylation incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Mus musculus (Mouse))
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50535640(CHEMBL4580738)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of mTOR in mouse TSC1-/- MEF cells assessed as inhibition of S6 Ser240/244 phosphorylation incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Mus musculus (Mouse))
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50535639(CHEMBL4563398)
Affinity DataIC50:  153nMAssay Description:Inhibition of mTOR in mouse TSC1-/- MEF cells assessed as inhibition of S6 Ser240/244 phosphorylation incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed