Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50010152
TargetSodium- and chloride-dependent glycine transporter 1(Human)
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50149871((R)-2-((3-(biphenyl-4-yloxy)-3-(4-fluorophenyl)pro...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human GlyT1 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake incubated for 10 mins at pH 7.4 by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50256745((2S)-2-amino-3-((2-(benzyloxy)phenyl)(3-fluorophen...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human GlyT2 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake at pH 7.5 by scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50535678(CHEMBL4439878)
Affinity DataIC50: 478nMAssay Description:Inhibition of human GlyT2 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake at pH 7.5 by scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50535680(CHEMBL4452842)
Affinity DataIC50: 518nMAssay Description:Inhibition of human GlyT2 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake at pH 7.5 by scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50149871((R)-2-((3-(biphenyl-4-yloxy)-3-(4-fluorophenyl)pro...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human GlyT2 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake at pH 7.5 by scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50535679(CHEMBL4566424)
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of human GlyT2 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake at pH 7.5 by scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50535678(CHEMBL4439878)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human GlyT1 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake incubated for 10 mins at pH 7.4 by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50535679(CHEMBL4566424)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human GlyT1 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake incubated for 10 mins at pH 7.4 by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
The University of Texas At El Paso

Curated by ChEMBL
LigandPNGBDBM50535680(CHEMBL4452842)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human GlyT1 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake incubated for 10 mins at pH 7.4 by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed