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Found 17 Enz. Inhib. hit(s) with all data for entry = 50007517
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50510079(CHEMBL4460827)
Affinity DataIC50:  10nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50510077(CHEMBL4451141)
Affinity DataIC50:  90nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50510087(CHEMBL4444637)
Affinity DataIC50:  200nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  200nMAssay Description:Inhibition of PDE4D2 (unknown origin) by preincubated for 30 mins before substrate addition and measured after 60 mins by IMAP TR-FRET phosphodiester...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50060922(CHEMBL3394769)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50510078(CHEMBL4584384)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human PDE4D2 catalytic domain (86 to 413 residues) expressed in Escherichia coli strain BL21 using [3H]cAMP as substrate after 15 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50510082(CHEMBL4434820)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of PDE4D2 (unknown origin) by preincubated for 30 mins before substrate addition and measured after 60 mins by IMAP TR-FRET phosphodiester...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50510088(CHEMBL4455061)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of PDE4D2 (unknown origin) by preincubated for 30 mins before substrate addition and measured after 60 mins by IMAP TR-FRET phosphodiester...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50510089(CHEMBL4557935)
Affinity DataIC50:  1.37E+4nMAssay Description:Inhibition of PDE4D2 (unknown origin) by preincubated for 30 mins before substrate addition and measured after 60 mins by IMAP TR-FRET phosphodiester...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50510084(CHEMBL4529248)
Affinity DataIC50:  1.95E+4nMAssay Description:Inhibition of PDE4D2 (unknown origin) by preincubated for 30 mins before substrate addition and measured after 60 mins by IMAP TR-FRET phosphodiester...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50510086(CHEMBL4467092)
Affinity DataIC50:  2.32E+4nMAssay Description:Inhibition of PDE4D2 (unknown origin) by preincubated for 30 mins before substrate addition and measured after 60 mins by IMAP TR-FRET phosphodiester...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50510081(CHEMBL4564393)
Affinity DataIC50:  2.46E+4nMAssay Description:Inhibition of PDE4D2 (unknown origin) by preincubated for 30 mins before substrate addition and measured after 60 mins by IMAP TR-FRET phosphodiester...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50510083(CHEMBL4567635)
Affinity DataIC50:  2.95E+4nMAssay Description:Inhibition of PDE4D2 (unknown origin) by preincubated for 30 mins before substrate addition and measured after 60 mins by IMAP TR-FRET phosphodiester...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50510080(CHEMBL4462925)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PDE4D2 (unknown origin) by preincubated for 30 mins before substrate addition and measured after 60 mins by IMAP TR-FRET phosphodiester...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50510076(CHEMBL4443860)
Affinity DataIC50:  3.21E+4nMAssay Description:Inhibition of PDE4D2 (unknown origin) by preincubated for 30 mins before substrate addition and measured after 60 mins by IMAP TR-FRET phosphodiester...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50510085(CHEMBL4554204)
Affinity DataIC50:  3.38E+4nMAssay Description:Inhibition of PDE4D2 (unknown origin) by preincubated for 30 mins before substrate addition and measured after 60 mins by IMAP TR-FRET phosphodiester...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed