Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50007519
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in leukotriene B4 synthesis using arachidonic acid substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50510095(CHEMBL4465694)
Affinity DataIC50:  400nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as reduction in PGE2 production using arachidonic acid substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50510097(CHEMBL4553272)
Affinity DataIC50:  800nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as reduction in PGE2 production using arachidonic acid substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50510098(CHEMBL4515706)
Affinity DataIC50:  900nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as reduction in PGE2 production using arachidonic acid substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50510098(CHEMBL4515706)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in leukotriene B4 synthesis using arachidonic acid substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50510095(CHEMBL4465694)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in leukotriene B4 synthesis using arachidonic acid substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50510097(CHEMBL4553272)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in leukotriene B4 synthesis using arachidonic acid substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGE2 production using arachidonic acid substrate by ELISAMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50510096(ARAHYPIN-5)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in leukotriene B4 synthesis using arachidonic acid substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50510097(CHEMBL4553272)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGE2 production using arachidonic acid substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50510095(CHEMBL4465694)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGE2 production using arachidonic acid substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as reduction in PGE2 production using arachidonic acid substrate by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50510099(CHEMBL4517895)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as reduction in PGE2 production using arachidonic acid substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50510096(ARAHYPIN-5)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as reduction in PGE2 production using arachidonic acid substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50510098(CHEMBL4515706)
Affinity DataIC50:  1.47E+4nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGE2 production using arachidonic acid substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50510096(ARAHYPIN-5)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGE2 production using arachidonic acid substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50510099(CHEMBL4517895)
Affinity DataIC50:  3.55E+4nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGE2 production using arachidonic acid substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed