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Found 8 Enz. Inhib. hit(s) with all data for entry = 50007371
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | CHEMBL76 | CHLOROQUINE PHOSPHATE | Chloro...)
Affinity DataIC50:  31.3nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50508928(CHEMBL4436660)
Affinity DataIC50:  49.7nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50508929(CHEMBL4515750)
Affinity DataIC50:  61.7nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50508927(CHEMBL4543845)
Affinity DataIC50:  81.7nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50508925(CHEMBL4437261)
Affinity DataIC50:  94.9nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50508926(CHEMBL4446041)
Affinity DataIC50:  128nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)
Affinity DataIC50:  140nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  144nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate incubated for 2 mins followed by substrate additionMore data for this Ligand-Target Pair