Compile Data Set for Download or QSAR
Report error Found 176 Enz. Inhib. hit(s) with all data for entry = 50008405
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518949BDBM50518949(CHEMBL4448131)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359538BDBM50359538(CHEMBL1235773)
Affinity DataIC50: 14nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518919BDBM50518919(CHEMBL4575906)
Affinity DataIC50: 20nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in enzyme-mediated supercoiling of relaxed plasmid by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518940BDBM50518940(CHEMBL4541988)
Affinity DataIC50: 20nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518915BDBM50518915(CHEMBL4583368)
Affinity DataIC50: 20nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518915BDBM50518915(CHEMBL4583368)
Affinity DataIC50: 40nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518948BDBM50518948(CHEMBL4574863)
Affinity DataIC50: 40nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050549BDBM50050549(GSK2140944 | Gepotidacin)
Affinity DataIC50: 47nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518940BDBM50518940(CHEMBL4541988)
Affinity DataIC50: 50nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518915BDBM50518915(CHEMBL4583368)
Affinity DataIC50: 100nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518948BDBM50518948(CHEMBL4574863)
Affinity DataIC50: 100nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518915BDBM50518915(CHEMBL4583368)
Affinity DataIC50: 100nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359538BDBM50359538(CHEMBL1235773)
Affinity DataIC50: 100nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518948BDBM50518948(CHEMBL4574863)
Affinity DataIC50: 100nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518940BDBM50518940(CHEMBL4541988)
Affinity DataIC50: 100nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518948BDBM50518948(CHEMBL4574863)
Affinity DataIC50: 100nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518949BDBM50518949(CHEMBL4448131)
Affinity DataIC50: 125nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518921BDBM50518921(CHEMBL4531538)
Affinity DataIC50: 140nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518924BDBM50518924(CHEMBL4533152)
Affinity DataIC50: 150nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518924BDBM50518924(CHEMBL4533152)
Affinity DataIC50: 200nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518911BDBM50518911(CHEMBL4530328)
Affinity DataIC50: 300nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518924BDBM50518924(CHEMBL4533152)
Affinity DataIC50: 300nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518911BDBM50518911(CHEMBL4530328)
Affinity DataIC50: 400nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518940BDBM50518940(CHEMBL4541988)
Affinity DataIC50: 400nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518939BDBM50518939(CHEMBL4531900)
Affinity DataIC50: 500nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050549BDBM50050549(GSK2140944 | Gepotidacin)
Affinity DataIC50: 600nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518911BDBM50518911(CHEMBL4530328)
Affinity DataIC50: 600nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518933BDBM50518933(CHEMBL4567626)
Affinity DataIC50: 600nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518928BDBM50518928(CHEMBL4544202)
Affinity DataIC50: 700nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518938BDBM50518938(CHEMBL4445613)
Affinity DataIC50: 800nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518925BDBM50518925(CHEMBL4438807)
Affinity DataIC50: 800nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518921BDBM50518921(CHEMBL4531538)
Affinity DataIC50: 830nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518918BDBM50518918(CHEMBL4569403)
Affinity DataIC50: 900nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518922BDBM50518922(CHEMBL4441397)
Affinity DataIC50: 900nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518944BDBM50518944(CHEMBL4537564)
Affinity DataIC50: 900nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518951BDBM50518951(CHEMBL4570423)
Affinity DataIC50: 900nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21690BDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393503BDBM50393503(CHEMBL2158050)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA measured after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518928BDBM50518928(CHEMBL4544202)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518941BDBM50518941(CHEMBL4465361)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518922BDBM50518922(CHEMBL4441397)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518918BDBM50518918(CHEMBL4569403)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518924BDBM50518924(CHEMBL4533152)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518926BDBM50518926(CHEMBL4536608)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518933BDBM50518933(CHEMBL4567626)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518922BDBM50518922(CHEMBL4441397)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518932BDBM50518932(CHEMBL4467826)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518913BDBM50518913(CHEMBL4575351)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518913BDBM50518913(CHEMBL4575351)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518941BDBM50518941(CHEMBL4465361)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
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