Found 61 Enz. Inhib. hit(s) with all data for entry = 50008122 
Affinity DataEC50: 710nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 7.20E+3nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 9.50E+3nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 8.10E+3nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 5.60E+3nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
Affinity DataEC50: 930nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 3.70E+3nMAssay Description:Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...More data for this Ligand-Target Pair
Affinity DataEC50: 73nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
Affinity DataEC50: 550nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
Affinity DataEC50: 910nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
Affinity DataEC50: 960nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
Affinity DataEC50: 910nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
Affinity DataEC50: 720nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
Affinity DataEC50: 690nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
Affinity DataEC50: 820nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
Affinity DataEC50: 320nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
Affinity DataEC50: 650nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
Affinity DataEC50: 500nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 7.30E+3nMAssay Description:Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 3.90E+3nMAssay Description:Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 5.80E+3nMAssay Description:Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 1.90E+3nMAssay Description:Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 2.80E+3nMAssay Description:Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 3.70E+3nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 6.40E+3nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 6.80E+3nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 1.10E+4nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 4.20E+3nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 2.30E+3nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 4.70E+3nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 4.70E+3nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 4.30E+3nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 2.50E+3nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 6.20E+3nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 900nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
Affinity DataEC50: 760nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.04E+3nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 3.50E+3nMAssay Description:Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 3.35E+4nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 4.60E+3nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
Affinity DataEC50: 950nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+3nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
Affinity DataEC50: 810nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
Affinity DataEC50: 550nMAssay Description:Inhibition of P-gp (unknown origin) expressed in MDCK-MDR1 cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM ...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 1.27E+4nMAssay Description:Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 1.01E+4nMAssay Description:Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 6.80E+3nMAssay Description:Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation incubated for 30 mins by calcein-AM dye b...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 2.30E+3nMAssay Description:Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as increase in Hoechst 33342 accumulation incubated for 30 mins by Hoechst 33342...More data for this Ligand-Target Pair
