Found 9 Enz. Inhib. hit(s) with all data for entry = 50009164 Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Capital Medical University
Curated by ChEMBL
Capital Medical University
Curated by ChEMBL
Affinity DataEC50: 1.17E+4nMAssay Description:Inhibition of PDK1 (unknown origin) using PDCE1 as substrate incubated for 30 mins by kinase-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Capital Medical University
Curated by ChEMBL
Capital Medical University
Curated by ChEMBL
Affinity DataEC50: 456nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged SUMO-fused PDK2 expressed in Escherichia coli BL-21 cells preincubated for 15 mins followed by...More data for this Ligand-Target Pair
3D Structure (crystal)Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Capital Medical University
Curated by ChEMBL
Capital Medical University
Curated by ChEMBL
Affinity DataEC50: 1.10E+3nMAssay Description:Inhibition of PDK2 (unknown origin) using PDCE1 as substrate incubated for 30 mins by kinase-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Capital Medical University
Curated by ChEMBL
Capital Medical University
Curated by ChEMBL
Affinity DataEC50: 5.20E+3nMAssay Description:Inhibition of PDK2 (unknown origin) using PDCE1 as substrate incubated for 30 mins by kinase-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Homo sapiens (Human))
Capital Medical University
Curated by ChEMBL
Capital Medical University
Curated by ChEMBL
Affinity DataEC50: 2.45E+4nMAssay Description:Inhibition of PDK3 (unknown origin) using PDCE1 as substrate incubated for 30 mins by kinase-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Capital Medical University
Curated by ChEMBL
Capital Medical University
Curated by ChEMBL
Affinity DataEC50: 6.70E+4nMAssay Description:Inhibition of PDK4 (unknown origin) using PDCE1 as substrate incubated for 30 mins by kinase-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Capital Medical University
Curated by ChEMBL
Capital Medical University
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Inhibition of PDK2 (unknown origin)More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Capital Medical University
Curated by ChEMBL
Capital Medical University
Curated by ChEMBL
Affinity DataEC50: 3.80E+3nMAssay Description:Inhibition of PDK2 (unknown origin) using PDCE1 as substrate incubated for 30 mins by kinase-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Capital Medical University
Curated by ChEMBL
Capital Medical University
Curated by ChEMBL
Affinity DataKd: 2.35E+3nMAssay Description:Binding affinity to PDK2 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
