Affinity DataKi: 0.0180nMAssay Description:Inhibition of wild-type BCL-2 (unknown origin) expressed in Escherichia coli BL21 cells using biotinylated BIMBH3 or BAXBH3 peptide by surface plasmo...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataKi: 0.0400nMAssay Description:Inhibition of TAMRA-labeled BIM BH3 peptide binding to human Mcl1 (171 to 327 residues) incubated for 120 mins by fluorescence polarizationMore data for this Ligand-Target Pair
Affinity DataKi: 0.0440nMAssay Description:Inhibition of His-tagged Bcl-2 (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataKi: 0.0500nMAssay Description:Inhibition of TAMRA-labeled BIM BH3 peptide binding to human Mcl1 (171 to 327 residues) incubated for 120 mins by fluorescence polarizationMore data for this Ligand-Target Pair
Affinity DataKi: <0.100nMAssay Description:Inhibition of His-tagged Bcl-2 (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Inhibition of TAMRA-labeled BIM BH3 peptide binding to human Mcl1 (171 to 327 residues) incubated for 120 mins by fluorescence polarizationMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of N-terminal GST-tagged-Mcl1 (E171 to G327) (unknown origin) expressed in Escherichia coli using HyLite Fluor 647-labeled Bim peptide C a...More data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Inhibition of wild-type BCL-2 (unknown origin) expressed in Escherichia coli BL21 cells using biotinylated BIMBH3 or BAXBH3 peptide by surface plasmo...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of FITC-labelled BAK peptide binding to human MBP-fused Mcl-1 (172 to 327 residues) expressed in Escherichia coli BL21 CodonPlus (DE3) RIL...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataKi: <1.20nMAssay Description:Displacement of fluorescein labelled Puma-BH3 peptide from C-terminal MBP-fused human Mcl-1 (173 to 321 residues) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Inhibition of FITC-labelled BAK peptide binding to human MBP-fused Mcl-1 (172 to 327 residues) expressed in Escherichia coli BL21 CodonPlus (DE3) RIL...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataKi: 55nMAssay Description:Inhibition of Mcl1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Inhibition of Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Mcl1 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human BCl2 expressed in Escherichia coli BL21 (DE3) pLysS cells by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of Bcl-xL (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of TAMRA-labeled BIM BH3 peptide binding to human Mcl1 (171 to 327 residues) incubated for 120 mins by fluorescence polarizationMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of Bcl-xL (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of fluorescein labelled Puma-BH3 peptide from human BCl2 expressed in Escherichia coli BL21 (DE3) pLysS cells incubated for 2 hrs by flu...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of TAMRA-labeled BIM BH3 peptide binding to human Mcl1 (171 to 327 residues) incubated for 120 mins by fluorescence polarizationMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of N-terminal GST-tagged-Mcl1 (E171 to G327) (unknown origin) expressed in Escherichia coli using HyLite Fluor 647-labeled Bim peptide C a...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of fluorescein labelled Puma-BH3 peptide from His-tagged-TEV fused human Mcl-1 incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of TAMRA-labeled BIM BH3 peptide binding to human Mcl1 (171 to 327 residues) incubated for 120 mins by fluorescence polarizationMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Displacement of fluorescein labelled Puma-BH3 peptide from human BCl2 expressed in Escherichia coli BL21 (DE3) pLysS cells incubated for 2 hrs by flu...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of N-terminal GST-tagged-Mcl1 (E171 to G327) (unknown origin) expressed in Escherichia coli using HyLite Fluor 647-labeled Bim peptide C a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of fluorescein labelled Puma-BH3 peptide from human BCl2 expressed in Escherichia coli BL21 (DE3) pLysS cells incubated for 2 hrs by flu...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Mcl1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of Mcl1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Normandie Univiversit�
Curated by ChEMBL
Normandie Univiversit�
Curated by ChEMBL
Affinity DataIC50: 5.20E+5nMAssay Description:Displacement of fluorescein labelled Puma-BH3 peptide from His-tagged-TEV fused human Mcl-1 incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair