TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using testosterone as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Positive allosteric modulator activity at mouse GLP-1R expressed in PSC-HEK293 cells in presence of EC20 level of GLP1(9-36)NH2 incubated for 30 mins...More data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Positive allosteric modulator activity at human GLP-1R expressed in PSC-HEK293 cells in presence of EC20 level of GLP1(9-36)NH2 incubated for 30 mins...More data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataEC50: 5nMAssay Description:Positive allosteric modulator activity at human GLP-1R expressed in PSC-HEK293 cells in presence of EC20 level of GLP1(9-36)NH2 incubated for 30 mins...More data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Positive allosteric modulator activity at GLP-1R in human 1.1B4 cells in presence of EC20 level of GLP1(9-36)NH2 incubated for 30 mins by HTRF cAMP a...More data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Positive allosteric modulator activity at GLP-1R in human 1.1B4 cells in presence of EC20 level of GLP1(9-36)NH2 incubated for 30 mins by HTRF cAMP a...More data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataEC50: 600nMAssay Description:Positive allosteric modulator activity at human GLP-1R expressed in PSC-HEK293 cells in presence of EC20 level of GLP1(9-36)NH2 incubated for 30 mins...More data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataEC50: 5nMAssay Description:Positive allosteric modulator activity at human GLP-1R expressed in PSC-HEK293 cells in presence of EC20 level of GLP1(9-36)NH2 incubated for 30 mins...More data for this Ligand-Target Pair