Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50007956
TargetCoagulation factor X(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50462575(CHEMBL4238121)
Affinity DataKi:  29nMAssay Description:Inhibition human FA10a using Boc-LeuGly-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProthrombin(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514426(CHEMBL4574713)
Affinity DataKi:  50nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514409(CHEMBL4549938)
Affinity DataKi:  600nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514425(CHEMBL4462026)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity to Staphylococcus aureus biotin protein ligaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD kinase 1(Listeria monocytogenes serovar 1/2a (strain ATCC B...)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514423(CHEMBL4552749)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of Listeria monocytogenes NAD kinase assessed as suppression of reduced NADP formation by yeast glucose-6-phosphate dehydrogenase coupled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM23234(1,2,5-oxadiazole, OXD2 | 4-amino-1,2,5-oxadiazole-...)
Affinity DataKi:  4.20E+5nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50232690(4-Aminomethyl-Benzamidine | CHEMBL187301)
Affinity DataKi:  6.80E+5nMAssay Description:Inhibition human FA10a using Boc-LeuGly-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514412(CHEMBL4462216)
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514411(CHEMBL4574617)
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514410(CHEMBL4566571)
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514419(CHEMBL4454339)
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514420(CHEMBL4459159)
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514421(CHEMBL4438181)
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514422(CHEMBL4466928)
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514424(CHEMBL4452459)
Affinity DataKi: >5.00E+6nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514418(CHEMBL4572188)
Affinity DataKi:  5.50E+6nMAssay Description:Inhibition human FA10a using Boc-LeuGly-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514408(CHEMBL4435351)
Affinity DataIC50:  10nMAssay Description:Inhibition of Photinus pyralis luciferase using ATP and D-luciferin in presence of Coenzyme A and DL-cysteine by luminescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514416(CHEMBL4466030)
Affinity DataIC50:  50nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514415(CHEMBL4527561)
Affinity DataIC50:  56nMAssay Description:Inhibition of human recombinant IDE pre-incubated for 10 mins before Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp substrate addition and measured after 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514406(CHEMBL4444391)
Affinity DataIC50:  60nMAssay Description:Inhibition of COX2 human HCA7 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514416(CHEMBL4466030)
Affinity DataIC50:  80nMAssay Description:Inhibition of COX2 human HCA7 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514406(CHEMBL4444391)
Affinity DataIC50:  90nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  90nMAssay Description:Inhibition of COX2 human HCA7 cellsMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514407(CHEMBL4483038)
Affinity DataIC50:  1.40E+3nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514413(CHEMBL4555061)
Affinity DataIC50:  2.90E+3nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 5B(Mus musculus)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514414(CHEMBL4439829)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of STAT5b in mouse BaF3/FLT3-ITD cells assessed as reduction in cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514414(CHEMBL4439829)
Affinity DataIC50:  3.70E+4nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothiapepsin(Cryphonectria parasitica)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514427(CHEMBL4452904)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of Cryphonectria parasitica Endothiapepsin using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 substrate by fluorescence screening assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 5B(Mus musculus)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514413(CHEMBL4555061)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibition of STAT5b in mouse BaF3/FLT3-ITD cells assessed as reduction in cell proliferationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 5B(Mus musculus)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514407(CHEMBL4483038)
Affinity DataIC50:  1.53E+5nMAssay Description:Inhibition of STAT5b in mouse BaF3/FLT3-ITD cells assessed as reduction in cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514428(CHEMBL4450233)
Affinity DataKd:  0.5nMAssay Description:Binding affinity to bovine carbonic anhydrase 2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50514417(CHEMBL4540374)
Affinity DataKd:  10nMAssay Description:Binding affinity to human COX2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50236140(4-ethynyl benzene sulfonamide | 4-ethynylbenzenesu...)
Affinity DataKd:  37nMAssay Description:Binding affinity to bovine carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed