TargetGlucocorticoid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GAL4-fused Glucocorticoid receptor (unknown origin) expressed in HEK293T cells incubated for 24 by BrightGlo reagent based assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GAL4-fused RXR LBD (unknown origin) expressed in HEK293T cells incubated for 24 by BrightGlo reagent based assayMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at androgen receptor (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 7nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 7nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 4.80E+3nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 27nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 480nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 4.84E+3nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 23nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 0.700nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 520nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 32nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GAL4-fused LXR LBD (unknown origin) expressed in HEK293T cells incubated for 24 by BrightGlo reagent based assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at PPARgamma (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 6.00E+3nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 145nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GAL4-fused PPARgamma (unknown origin) expressed in HEK293T cells incubated for 24 by BrightGlo reagent based assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 44nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at Progesterone receptor (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 24nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 71nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 280nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at ERalpha (unknown origin) incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 2.84E+3nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 13nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 2.17E+3nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 150nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 2.70E+3nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 6.00E+3nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 530nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 25nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 38nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 171nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 1.00E+4nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 186nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 24nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute Of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair