Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50011158
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545382(CHEMBL4646450)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545379(CHEMBL4645010)
Affinity DataIC50:  5nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545380(CHEMBL4645458)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545383(CHEMBL4636355)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545382(CHEMBL4646450)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM6309(6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-y...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human CDK4/cyclin-D1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545379(CHEMBL4645010)
Affinity DataIC50:  13nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545380(CHEMBL4645458)
Affinity DataIC50:  16nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545381(CHEMBL4649032)
Affinity DataIC50:  16nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545383(CHEMBL4636355)
Affinity DataIC50:  16nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetG1/S-specific cyclin-D2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM6309(6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-y...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human CDK6/cyclin-D2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545384(CHEMBL4548417)
Affinity DataIC50:  20nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545378(CHEMBL4638298)
Affinity DataIC50:  32nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM6309(6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-y...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545376(CHEMBL4638166)
Affinity DataIC50:  32nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545381(CHEMBL4649032)
Affinity DataIC50:  40nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545377(CHEMBL4640158)
Affinity DataIC50:  40nMAssay Description:Inhibition of human CDK4/cyclin-D1 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545384(CHEMBL4548417)
Affinity DataIC50:  50nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM6309(6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-y...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545378(CHEMBL4638298)
Affinity DataIC50:  126nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545377(CHEMBL4640158)
Affinity DataIC50:  158nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545376(CHEMBL4638166)
Affinity DataIC50:  200nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50545376(CHEMBL4638166)
Affinity DataIC50:  200nMAssay Description:Inhibition of human CDK6/cyclin-D3 using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed