Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50011170
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Andhra University

Curated by ChEMBL
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of recombinant human PDE4B expressed in baculovirus infected Sf9 cells using [3H] cAMP as substrate after 30 min by scintillation proximit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Andhra University

Curated by ChEMBL
LigandPNGBDBM50545410(CHEMBL4635395)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of recombinant human PDE4B expressed in baculovirus infected Sf9 cells using [3H] cAMP as substrate after 30 min by scintillation proximit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Andhra University

Curated by ChEMBL
LigandPNGBDBM50545411(CHEMBL4641594)
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of recombinant human PDE4B expressed in baculovirus infected Sf9 cells using [3H] cAMP as substrate after 30 min by scintillation proximit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Andhra University

Curated by ChEMBL
LigandPNGBDBM50545412(CHEMBL4640592)
Affinity DataIC50: 4.13E+3nMAssay Description:Inhibition of recombinant human PDE4B expressed in baculovirus infected Sf9 cells using [3H] cAMP as substrate after 30 min by scintillation proximit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Andhra University

Curated by ChEMBL
LigandPNGBDBM50545413(CHEMBL4648824)
Affinity DataIC50: 4.48E+3nMAssay Description:Inhibition of recombinant human PDE4B expressed in baculovirus infected Sf9 cells using [3H] cAMP as substrate after 30 min by scintillation proximit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
LigandPNGBDBM50545410(CHEMBL4635395)
Affinity DataIC50: 5.81E+3nMAssay Description:Inhibition of PDE4 (unknown origin) assessed as inhibition of TNF-alpha releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed