Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50009347
TargetExportin-1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50527778(KPT-330 | Selinexor | Xpovio | US20240376114, Comp...)
Affinity DataKd:  19nMAssay Description:Binding affinity to recombinant His-tagged CRM1 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetExportin-1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50527779(CHEMBL4440028)
Affinity DataKd:  27nMAssay Description:Binding affinity to recombinant His-tagged CRM1 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetExportin-1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50527779(CHEMBL4440028)
Affinity DataIC50: 151nMAssay Description:Inhibition of CRM1 in human HCT-15 cells assessed as reduction in cell viability incubated for 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetExportin-1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50527777(CHEMBL4458289)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of nuclear CRM1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50527779(CHEMBL4440028)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in human HEK293 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed