Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50010409
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538591(CHEMBL4648775)
Affinity DataIC50:  390nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538602(CHEMBL4641044)
Affinity DataIC50:  490nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538586(CHEMBL4637550)
Affinity DataIC50:  550nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538589(CHEMBL4634549)
Affinity DataIC50:  550nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538595(CHEMBL4645086)
Affinity DataIC50:  560nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538601(CHEMBL4649501)
Affinity DataIC50:  610nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538600(CHEMBL4642247)
Affinity DataIC50:  700nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538594(CHEMBL4635941)
Affinity DataIC50:  740nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538592(CHEMBL4646045)
Affinity DataIC50:  750nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538599(CHEMBL4637515)
Affinity DataIC50:  760nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538593(CHEMBL4634981)
Affinity DataIC50:  760nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538597(CHEMBL4647036)
Affinity DataIC50:  780nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538584(CHEMBL4643278)
Affinity DataIC50:  820nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538596(CHEMBL4637809)
Affinity DataIC50:  820nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538590(CHEMBL4641589)
Affinity DataIC50:  990nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538585(CHEMBL4641324)
Affinity DataIC50:  1.10E+3nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538598(CHEMBL4634027)
Affinity DataIC50:  1.18E+3nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538587(CHEMBL4634838)
Affinity DataIC50:  1.36E+3nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538588(CHEMBL4642196)
Affinity DataIC50:  1.97E+3nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM81939(CAS_52-53-9 | NSC_62969 | VERAPAMIL)
Affinity DataIC50:  2.98E+3nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538595(CHEMBL4645086)
Affinity DataEC50:  37nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as concentration required to show half of DOX IC50 incubated for 48 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538591(CHEMBL4648775)
Affinity DataEC50:  103nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as concentration required to show half of DOX IC50 incubated for 48 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50538601(CHEMBL4649501)
Affinity DataEC50:  51nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as concentration required to show half of DOX IC50 incubated for 48 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed