Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50012729
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056998BDBM50056998(Meloxicam sodium | 4-Hydroxy-2-methyl-1,1-dioxo-1,...)
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559766BDBM50559766(CHEMBL4740435)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056998BDBM50056998(Meloxicam sodium | 4-Hydroxy-2-methyl-1,1-dioxo-1,...)
Affinity DataIC50: 3.12E+4nMAssay Description:Inhibition of human recombinant COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated for 10 mins measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559765BDBM50559765(CHEMBL4787953)
Affinity DataIC50: 7.68E+4nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559782BDBM50559782(CHEMBL4778555)
Affinity DataIC50: 9.88E+4nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559765BDBM50559765(CHEMBL4787953)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated for 10 mins measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559769BDBM50559769(CHEMBL4754867)
Affinity DataIC50: 1.06E+5nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559778BDBM50559778(CHEMBL4750551)
Affinity DataIC50: 1.15E+5nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559766BDBM50559766(CHEMBL4740435)
Affinity DataIC50: 1.58E+5nMAssay Description:Inhibition of human recombinant COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated for 10 mins measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559771BDBM50559771(CHEMBL4792565)
Affinity DataIC50: 1.67E+5nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559777BDBM50559777(CHEMBL4754793)
Affinity DataIC50: 1.94E+5nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559774BDBM50559774(CHEMBL4763976)
Affinity DataIC50: 2.17E+5nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559783BDBM50559783(CHEMBL4745894)
Affinity DataIC50: 2.28E+5nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559768BDBM50559768(CHEMBL4782861)
Affinity DataIC50: 2.73E+5nMAssay Description:Inhibition of human recombinant COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated for 10 mins measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559767BDBM50559767(CHEMBL4799825)
Affinity DataIC50: 2.76E+5nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559779BDBM50559779(CHEMBL4779383)
Affinity DataIC50: 2.76E+5nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559773BDBM50559773(CHEMBL4748665)
Affinity DataIC50: 2.88E+5nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559770BDBM50559770(CHEMBL4789246)
Affinity DataIC50: 2.92E+5nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559781BDBM50559781(CHEMBL4763941)
Affinity DataIC50: 3.20E+5nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559768BDBM50559768(CHEMBL4782861)
Affinity DataIC50: 4.24E+5nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559775BDBM50559775(CHEMBL4796545)
Affinity DataIC50: 4.45E+5nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559776BDBM50559776(CHEMBL4777820)
Affinity DataIC50: 4.60E+5nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559780BDBM50559780(CHEMBL4796006)
Affinity DataIC50: 4.95E+5nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559767BDBM50559767(CHEMBL4799825)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human recombinant COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated for 10 mins measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559772BDBM50559772(CHEMBL4791001)
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of human recombinant COX2 assessed as reduction in PGH2 formation using arachidonic acid as substrate preincubated for 10 mins measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed