Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50010741
TargetMitogen-activated protein kinase 14(Human)
Federal University of Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50425360(CHEMBL2316207)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p38alpha MAPK expressed in baculovirus infected Sf9 insect cells using p38 peptide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Federal University of Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50425360(CHEMBL2316207)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of NanoBRET kinase tracer K4 binding to full-length human C-terminal NanoLuc-tagged p38alpha MAPK expressed in HEK293T cells incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Federal University of Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50541590(CHEMBL4646557)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of NanoBRET kinase tracer K4 binding to full-length human C-terminal NanoLuc-tagged p38alpha MAPK expressed in HEK293T cells incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Federal University of Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50541587(CHEMBL4640746)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of NanoBRET kinase tracer K4 binding to full-length human C-terminal NanoLuc-tagged p38alpha MAPK expressed in HEK293T cells incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Federal University of Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50541591(CHEMBL4648755)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p38alpha MAPK expressed in baculovirus infected Sf9 insect cells using p38 peptide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Federal University of Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50541588(CHEMBL4645084)
Affinity DataIC50: 16nMAssay Description:Inhibition of NanoBRET kinase tracer K4 binding to full-length human C-terminal NanoLuc-tagged p38alpha MAPK expressed in HEK293T cells incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Federal University of Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50541589(CHEMBL4642910)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p38alpha MAPK expressed in baculovirus infected Sf9 insect cells using p38 peptide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Federal University of Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50541587(CHEMBL4640746)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p38alpha MAPK expressed in baculovirus infected Sf9 insect cells using p38 peptide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Federal University of Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50541590(CHEMBL4646557)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p38alpha MAPK expressed in baculovirus infected Sf9 insect cells using p38 peptide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Federal University of Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50541588(CHEMBL4645084)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p38alpha MAPK expressed in baculovirus infected Sf9 insect cells using p38 peptide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Federal University of Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50541589(CHEMBL4642910)
Affinity DataIC50: 30nMAssay Description:Inhibition of NanoBRET kinase tracer K4 binding to full-length human C-terminal NanoLuc-tagged p38alpha MAPK expressed in HEK293T cells incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Federal University of Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50425360(CHEMBL2316207)
Affinity DataIC50: 38nMAssay Description:Inhibition of p38alpha MAPK in human whole blood assessed as reduction in LPS-induced TNFalpha production preincubated for 2.5 hrs followed by LPS st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Federal University of Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50541591(CHEMBL4648755)
Affinity DataIC50: 43nMAssay Description:Inhibition of p38alpha MAPK in human whole blood assessed as reduction in LPS-induced TNFalpha production preincubated for 2.5 hrs followed by LPS st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Federal University of Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50541587(CHEMBL4640746)
Affinity DataIC50: 47nMAssay Description:Inhibition of p38alpha MAPK in human whole blood assessed as reduction in LPS-induced TNFalpha production preincubated for 2.5 hrs followed by LPS st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Federal University of Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50541590(CHEMBL4646557)
Affinity DataIC50: 101nMAssay Description:Inhibition of p38alpha MAPK in human whole blood assessed as reduction in LPS-induced TNFalpha production preincubated for 2.5 hrs followed by LPS st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Federal University of Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50541588(CHEMBL4645084)
Affinity DataIC50: 276nMAssay Description:Inhibition of p38alpha MAPK in human whole blood assessed as reduction in LPS-induced TNFalpha production preincubated for 2.5 hrs followed by LPS st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Federal University of Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50541589(CHEMBL4642910)
Affinity DataIC50: 490nMAssay Description:Inhibition of p38alpha MAPK in human whole blood assessed as reduction in LPS-induced TNFalpha production preincubated for 2.5 hrs followed by LPS st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed