Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50018339
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50443274(CHEMBL5285380 | US12220415, Compound KAC-034)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant Wee1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50164160(4-{4-[6-(2,6-Dichloro-phenyl)-8-methyl-7-oxo-7,8-d...)
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50443272(CHEMBL5283663 | US12220415, Compound KAC-019)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of recombinant Wee1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50240826(AZD-1775 | MK-1775 | US11124518, Example AZD1775 |...)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of recombinant human Wee1 incubated for 30 mins by liquid scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50506983(CHEMBL4529533 | US12220415, Compound CM-169)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of recombinant Wee1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50443273(CHEMBL5291046 | US12220415, Compound CM-181)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant Wee1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50443275(CHEMBL5273914)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant Wee1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50164121(2-{4-[6-(2,6-Dichloro-phenyl)-8-methyl-7-oxo-7,8-d...)
Affinity DataIC50: 13nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50164136(6-(2,6-Dimethyl-phenyl)-8-methyl-2-phenylamino-8H-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM31545(Milciclib | pyrazolo[4,3-h]quinazoline-3-carboxami...)
Affinity DataKd:  14nMAssay Description:Binding affinity to Wee1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50164162(2-[4-(2-Diethylamino-ethoxy)-phenylamino]-6-(2,6-d...)
Affinity DataIC50: 23nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM3096(6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)etho...)
Affinity DataIC50: 24nMAssay Description:Inhibition of Wee1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM3071(2-anilino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,...)
Affinity DataIC50: 24nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50565801(CHEMBL4780868)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant Wee1 (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM3105(4-(4-{[6-(2,6-dichlorophenyl)-8-methyl-7-oxo-7H,8H...)
Affinity DataIC50: 32nMAssay Description:Inhibition of Wee1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM3105(4-(4-{[6-(2,6-dichlorophenyl)-8-methyl-7-oxo-7H,8H...)
Affinity DataIC50: 32nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50164108(4-{4-[6-(2,6-Dichloro-3-hydroxy-phenyl)-8-methyl-7...)
Affinity DataIC50: 40nMAssay Description:Inhibition of Wee1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataKd:  44nMAssay Description:Binding affinity to Wee1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase Chk1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM3096(6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)etho...)
Affinity DataIC50: 72nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50240828(CHEMBL4067978)
Affinity DataKd:  78nMAssay Description:Binding affinity to Wee1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50240827(CHEMBL4075828)
Affinity DataKd:  79nMAssay Description:Binding affinity to Wee1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50164160(4-{4-[6-(2,6-Dichloro-phenyl)-8-methyl-7-oxo-7,8-d...)
Affinity DataIC50: 86nMAssay Description:Inhibition of Wee1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50164108(4-{4-[6-(2,6-Dichloro-3-hydroxy-phenyl)-8-methyl-7...)
Affinity DataIC50: 99nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50164121(2-{4-[6-(2,6-Dichloro-phenyl)-8-methyl-7-oxo-7,8-d...)
Affinity DataIC50: 120nMAssay Description:Inhibition of Wee1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50164143(2-[4-(2-Diethylamino-ethoxy)-phenylamino]-6-(2,6-d...)
Affinity DataIC50: 360nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50164143(2-[4-(2-Diethylamino-ethoxy)-phenylamino]-6-(2,6-d...)
Affinity DataIC50: 540nMAssay Description:Inhibition of Wee1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50164123(6-(2-Chloro-phenyl)-2-[4-(2-diethylamino-ethoxy)-p...)
Affinity DataIC50: 550nMAssay Description:Inhibition of Wee1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50164136(6-(2,6-Dimethyl-phenyl)-8-methyl-2-phenylamino-8H-...)
Affinity DataIC50: 990nMAssay Description:Inhibition of Wee1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50164162(2-[4-(2-Diethylamino-ethoxy)-phenylamino]-6-(2,6-d...)
Affinity DataIC50: 990nMAssay Description:Inhibition of Wee1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM3071(2-anilino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Wee1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50443276(CHEMBL5272317)
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of human full length N-terminal GST tagged Wee1 expressed in E coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50164123(6-(2-Chloro-phenyl)-2-[4-(2-diethylamino-ethoxy)-p...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed