Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50012246
TargetDNA topoisomerase 2-alpha(Human)
Alma Mater Studiorum-Universit£

Curated by ChEMBL
LigandPNGBDBM50555892(CHEMBL4745205)
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alpha assessed as suppression of decatenation using catenated kinetoplast DNA as substrate measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Alma Mater Studiorum-Universit£

Curated by ChEMBL
LigandPNGBDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataIC50: 6.83E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alpha assessed as suppression of decatenation using catenated kinetoplast DNA as substrate measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha(Human)
Alma Mater Studiorum-Universit£

Curated by ChEMBL
LigandPNGBDBM50555891(CHEMBL4756707)
Affinity DataIC50: 1.14E+5nMAssay Description:Inhibition of human DNA topoisomerase 2alpha assessed as suppression of decatenation using catenated kinetoplast DNA as substrate measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Alma Mater Studiorum-Universit£

Curated by ChEMBL
LigandPNGBDBM50555893(CHEMBL4747945)
Affinity DataIC50: 1.38E+5nMAssay Description:Inhibition of human DNA topoisomerase 2alpha assessed as suppression of decatenation using catenated kinetoplast DNA as substrate measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed