Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50018342
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 206061BDBM206061(US9255106, S3)
Affinity DataIC50: 0.740nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453726BDBM50453726(CHEMBL3919533)
Affinity DataIC50: 0.830nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446130BDBM50446130(AG-014699 | AG-14447 | Rucaparib | RUCAPARIB CAMSY...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 209857BDBM209857(US9273052, 19 | US9566277, 19)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PARP1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536936BDBM50536936(CHEMBL4584534)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536936BDBM50536936(CHEMBL4584534)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446130BDBM50446130(AG-014699 | AG-14447 | Rucaparib | RUCAPARIB CAMSY...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165486BDBM50165486(KU-58684 | 1-[2-Fluoro-5-(4-oxo-3,4-dihydro-phthal...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453725BDBM50453725(CHEMBL5284183)
Affinity DataKi:  5.60nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093374BDBM50093374(2-(4-Hydroxy-phenyl)-1H-benzoimidazole-4-carboxyli...)
Affinity DataKi:  6nMAssay Description:Inhibition of human full length PARP1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27119BDBM27119(ABT472 | 2-(1-propylpiperidin-4-yl)-1H-1,3-benzodi...)
Affinity DataKi:  8nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165486BDBM50165486(KU-58684 | 1-[2-Fluoro-5-(4-oxo-3,4-dihydro-phthal...)
Affinity DataKi:  12nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453722BDBM50453722(CHEMBL5283272)
Affinity DataIC50: 19nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27497BDBM27497(2-Dimethylamino-N-(6-oxo-5,6-dihydro-phenanthridin...)
Affinity DataIC50: 20nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453724BDBM50453724(CHEMBL5268593)
Affinity DataIC50: 140nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27682BDBM27682(5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one | CHE...)
Affinity DataIC50: 150nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27502BDBM27502(CHEMBL127336 | 3,4-dihydro-5-(4-(1-piperidinyl)but...)
Affinity DataIC50: 150nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453721BDBM50453721(CHEMBL133694)
Affinity DataIC50: 240nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27500BDBM27500(Phenanthridone | 5H-Phenanthridin-6-one (PTD) | 5H...)
Affinity DataIC50: 300nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453723BDBM50453723(CHEMBL5283140)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27506BDBM27506(CHEMBL81977 | 3-aminobenzamide | 3-AB)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106188BDBM50106188(cid_98487 | CHEMBL123978 | 3-Methoxy-benzamide)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27507BDBM27507(pyridine-3-carboxamide | nicotinamide | 3-Pyridine...)
Affinity DataIC50: 2.10E+5nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed