Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50011468
TargetSodium channel protein type 10 subunit alpha(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50547925(CHEMBL4798938 | US12441703, Compound 320)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50547926(CHEMBL4753280 | US12441703, Compound 323)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50547929(CHEMBL4744908 | US12441703, Compound 326)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50547924(CHEMBL4750365 | US12441703, Compound 309)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50547928(CHEMBL4787299 | US12441703, Compound 325)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50547927(CHEMBL4756380 | US12441703, Compound 324)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50547930(CHEMBL4782190 | US12441703, Compound 352)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50547922(CHEMBL4761578 | US12441703, Compound 194)
Affinity DataIC50: 2nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50547921(CHEMBL4785523 | US12441703, Compound 191)
Affinity DataIC50: 2nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50547923(CHEMBL4763419 | US12441703, Compound 305)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50547919(CHEMBL4764805 | US12441703, Compound 147)
Affinity DataIC50: 3nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50547920(CHEMBL4759624 | US12441703, Compound 151)
Affinity DataIC50: 4nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells applied electrical stimulus 10 Hz for 10 seconds measuring relaxation to the resting state followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed