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Found 14 Enz. Inhib. hit(s) with all data for entry = 50013693
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM23415(5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  210nMAssay Description:Inhibition of recombinant N-terminal GST/His6-tagged human FLT3 ITD mutant (571 to 993 residues) expressed in Sf9 insect cells incubated for 1 hr by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  230nMAssay Description:Inhibition of recombinant His-tagged human FLT3 D835Y mutant (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50092613(Salvigenin)
Affinity DataIC50:  290nMAssay Description:Inhibition of recombinant His-tagged human FLT3 D835Y mutant (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  390nMAssay Description:Inhibition of recombinant N-terminal GST/His6-tagged human FLT3 ITD mutant (571 to 993 residues) expressed in Sf9 insect cells incubated for 1 hr by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50049395(5,7,4'-Trihydroxy-6-methoxyflavone | 5,7-Dihydroxy...)
Affinity DataIC50:  440nMAssay Description:Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substrate incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50092613(Salvigenin)
Affinity DataIC50:  550nMAssay Description:Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substrate incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50092613(Salvigenin)
Affinity DataIC50:  580nMAssay Description:Inhibition of recombinant N-terminal GST/His6-tagged human FLT3 ITD mutant (571 to 993 residues) expressed in Sf9 insect cells incubated for 1 hr by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50064896(4,5-Dihydroxy-6-methoxy-2-(4-methoxy-phenyl)-chrom...)
Affinity DataIC50:  580nMAssay Description:Inhibition of recombinant His-tagged human FLT3 D835Y mutant (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50064896(4,5-Dihydroxy-6-methoxy-2-(4-methoxy-phenyl)-chrom...)
Affinity DataIC50:  650nMAssay Description:Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substrate incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50064896(4,5-Dihydroxy-6-methoxy-2-(4-methoxy-phenyl)-chrom...)
Affinity DataIC50:  880nMAssay Description:Inhibition of recombinant N-terminal GST/His6-tagged human FLT3 ITD mutant (571 to 993 residues) expressed in Sf9 insect cells incubated for 1 hr by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM23415(5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  880nMAssay Description:Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substrate incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM23415(5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant His-tagged human FLT3 D835Y mutant (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50344054(3',5-dihydroxy-4',6,7-trimethoxy flavone | 6-metho...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substrate incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50187658(4',5-dihydroxy-7-methoxy flavone | 4',5-dihydroxy-...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substrate incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed