Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50011648
TargetToll-like receptor 8(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549724(CHEMBL4799678)
Affinity DataIC50:  1nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB and AP-1 activation measured after 20 hrs by qu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 8(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549725(CHEMBL4745246)
Affinity DataIC50:  2nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB and AP-1 activation measured after 20 hrs by qu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549723(CHEMBL4755291)
Affinity DataIC50:  3nMAssay Description:Inhibition of human TLR7 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB and AP-1 activation measured after 20 hrs by qu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 8(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549727(CHEMBL4760220)
Affinity DataIC50: <3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB and AP-1 activation measured after 20 hrs by qu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 8(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549723(CHEMBL4755291)
Affinity DataIC50:  4nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB and AP-1 activation measured after 20 hrs by qu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 8(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549726(CHEMBL4747784)
Affinity DataIC50:  4nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB and AP-1 activation measured after 20 hrs by qu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549724(CHEMBL4799678)
Affinity DataIC50:  4nMAssay Description:Inhibition of human TLR7 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB and AP-1 activation measured after 20 hrs by qu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 8(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549722(CHEMBL4795549)
Affinity DataIC50:  6nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB and AP-1 activation measured after 20 hrs by qu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549726(CHEMBL4747784)
Affinity DataIC50:  6nMAssay Description:Inhibition of human TLR7 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB and AP-1 activation measured after 20 hrs by qu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549725(CHEMBL4745246)
Affinity DataIC50:  6nMAssay Description:Inhibition of human TLR7 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB and AP-1 activation measured after 20 hrs by qu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549722(CHEMBL4795549)
Affinity DataIC50:  7nMAssay Description:Inhibition of human TLR7 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB and AP-1 activation measured after 20 hrs by qu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549727(CHEMBL4760220)
Affinity DataIC50:  7nMAssay Description:Inhibition of human TLR7 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB and AP-1 activation measured after 20 hrs by qu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549726(CHEMBL4747784)
Affinity DataIC50:  47nMAssay Description:Inhibition of human TLR9 expressed in HEK-Blue cells assessed as inhibition of ODN2006-induced NF-kappaB and AP-1 activation measured after 20 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549725(CHEMBL4745246)
Affinity DataIC50:  50nMAssay Description:Inhibition of human TLR9 expressed in HEK-Blue cells assessed as inhibition of ODN2006-induced NF-kappaB and AP-1 activation measured after 20 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549724(CHEMBL4799678)
Affinity DataIC50:  50nMAssay Description:Inhibition of human TLR9 expressed in HEK-Blue cells assessed as inhibition of ODN2006-induced NF-kappaB and AP-1 activation measured after 20 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549727(CHEMBL4760220)
Affinity DataIC50:  54nMAssay Description:Inhibition of human TLR9 expressed in HEK-Blue cells assessed as inhibition of ODN2006-induced NF-kappaB and AP-1 activation measured after 20 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549722(CHEMBL4795549)
Affinity DataIC50:  70nMAssay Description:Inhibition of human TLR9 expressed in HEK-Blue cells assessed as inhibition of ODN2006-induced NF-kappaB and AP-1 activation measured after 20 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50549723(CHEMBL4755291)
Affinity DataIC50:  81nMAssay Description:Inhibition of human TLR9 expressed in HEK-Blue cells assessed as inhibition of ODN2006-induced NF-kappaB and AP-1 activation measured after 20 hrs by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed