Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 50022559
Affinity DataIC50: 24.5nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 54.2nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataKd: 97nMAssay Description:Binding affinity to biotinylated SMYD3 (unknown origin) assessed as dissociation constant using S-adenosyl-l-methionine as substrate by surface plasm...More data for this Ligand-Target Pair
Affinity DataKd: 133nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 177nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 183nMAssay Description:Inhibition of SMYD3 catalytic inactive mutant co-expressed with HA-tagged MAP3K2 transfected in human HeLa cells assessed as reduction of MAP3K2-K260...More data for this Ligand-Target Pair
Affinity DataIC50: 201nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 252nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 259nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 396nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 459nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 493nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 763nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 832nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+3nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+3nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.51E+3nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.85E+3nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.97E+3nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.33E+3nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.53E+3nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.64E+3nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 5.56E+3nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 5.71E+3nMAssay Description:Inhibition of T-Fyn (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Binding affinity to recombinant human SMYD3 expressed in Escherichia coli assessed as catalytic inhibition using DYDNPIFEKFGKGGTYPRRYHVSYHGK-Biotin a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of RSK4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDGFR beta (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of p38alpha (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NUAK1 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of TBK1 (unknown origin) in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Tak1 (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Tak1 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human TRK-AMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of FLT4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GST-tagged ERK5 catalytic domain (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of IRAK1 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human PIP4K2AMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human DYRK1aMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GSK-3-beta (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MEK5 (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MAP4K1 (unknown origin) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of KDR (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of IRAK4 (unknown origin) in BGG-buffer in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse DGK alpha by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MST1 (unknown origin)More data for this Ligand-Target Pair

3D Structure (crystal)





















