Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50017406
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50541592(CHEMBL3187788)
Affinity DataIC50: 4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50457815(CHEMBL4211840)
Affinity DataIC50: 10nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50429614(CHEMBL2334589)
Affinity DataIC50: 40nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601633(CHEMBL5196202)
Affinity DataIC50: 200nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601626(CHEMBL5198459)
Affinity DataIC50: 251nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601631(CHEMBL5175837)
Affinity DataIC50: 316nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601641(CHEMBL5182375)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601627(CHEMBL5196977)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601632(CHEMBL5170825)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601628(CHEMBL5197109)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601637(CHEMBL5206628)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601624(CHEMBL5198316)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601619(CHEMBL5185097)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601640(CHEMBL5175595)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601629(CHEMBL5182501)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601635(CHEMBL5181977)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601634(CHEMBL5203009)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601636(CHEMBL5194484)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601630(CHEMBL5182228)
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601638(CHEMBL5190105)
Affinity DataIC50: 7.94E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601639(CHEMBL5175142)
Affinity DataIC50: 7.94E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601625(CHEMBL5190943)
Affinity DataIC50: 7.94E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601621(CHEMBL5190680)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601620(CHEMBL5203081)
Affinity DataIC50: 3.98E+5nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601622(CHEMBL5192481)
Affinity DataIC50: 5.01E+5nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Newcastle University Centre For Cancer

Curated by ChEMBL
LigandPNGBDBM50601623(CHEMBL5204146)
Affinity DataIC50: 5.01E+5nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed