Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50016399
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594691BDBM50594691(CHEMBL5176593)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of 2-MeS-ADP induced P2Y12 (unknown origin) signalling expressed in CHO cells membrane incubated for 45 mins by 35S-GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594685BDBM50594685(CHEMBL5184268)
Affinity DataIC50: 1nMAssay Description:Displacement of tritium-labeled 2MeSADP from human P2Y12 expressed in CHO cells measured after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594684BDBM50594684(CHEMBL5179719)
Affinity DataIC50: 1nMAssay Description:Displacement of tritium-labeled 2MeSADP from human P2Y12 expressed in CHO cells measured after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594687BDBM50594687(CHEMBL5173489)
Affinity DataIC50: 1nMAssay Description:Displacement of tritium-labeled 2MeSADP from human P2Y12 expressed in CHO cells measured after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594686BDBM50594686(CHEMBL5195237)
Affinity DataIC50: 1nMAssay Description:Displacement of tritium-labeled 2MeSADP from human P2Y12 expressed in CHO cells measured after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594689BDBM50594689(CHEMBL5203416)
Affinity DataIC50: 1nMAssay Description:Displacement of tritium-labeled 2MeSADP from human P2Y12 expressed in CHO cells measured after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594688BDBM50594688(CHEMBL5192953)
Affinity DataIC50: 1nMAssay Description:Displacement of tritium-labeled 2MeSADP from human P2Y12 expressed in CHO cells measured after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594682BDBM50594682(CHEMBL5196387)
Affinity DataIC50: 2.80nMAssay Description:Displacement of tritium-labeled 2MeSADP from human P2Y12 expressed in CHO cells measured after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594681BDBM50594681(CHEMBL5188874)
Affinity DataIC50: 3nMAssay Description:Displacement of tritium-labeled 2MeSADP from human P2Y12 expressed in CHO cells measured after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 119428BDBM119428(US8669266, 679)
Affinity DataIC50: 3nMAssay Description:Displacement of [33P]2MeSADP from human P2Y12 expressed in CHO cell membranes preincubated for 15 mins followed by [33P]2MeSADP addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594677BDBM50594677(CHEMBL5207212)
Affinity DataIC50: 10nMAssay Description:Displacement of [33P]2MeSADP from human P2Y12 expressed in CHO cell membranes preincubated for 15 mins followed by [33P]2MeSADP addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594678BDBM50594678(CHEMBL5190693)
Affinity DataIC50: 10nMAssay Description:Displacement of [33P]2MeSADP from human P2Y12 expressed in CHO cell membranes preincubated for 15 mins followed by [33P]2MeSADP addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50336780BDBM50336780(sodium 1-amino-4-(3-amino-2-methylphenylamino)-9,1...)
Affinity DataKi:  25nMAssay Description:Binding affinity to human P2Y12 expressed in astrocytoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594679BDBM50594679(CHEMBL5170672)
Affinity DataIC50: 30nMAssay Description:Displacement of [33P]2MeSADP from human P2Y12 expressed in CHO cell membranes preincubated for 15 mins followed by [33P]2MeSADP addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594683BDBM50594683(CHEMBL5204363)
Affinity DataIC50: 34nMAssay Description:Displacement of tritium-labeled 2MeSADP from human P2Y12 expressed in CHO cells measured after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50397204BDBM50397204(ELINOGREL)
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]2MeSADP from human P2Y12 preincubated for 5 mins followed by [3H]2MeSADP addition and measured after 15 mins by scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268918BDBM50268918(1-Amino-2-methyl-4-[4-phenylamino-3-sulfophenylami...)
Affinity DataKi:  51nMAssay Description:Binding affinity to human P2Y12 expressed in astrocytoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594680BDBM50594680(CHEMBL5207480)
Affinity DataIC50: 61nMAssay Description:Displacement of tritium-labeled 2MeSADP from human P2Y12 expressed in CHO cells measured after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50237558BDBM50237558(CHEMBL1671994)
Affinity DataKi:  63nMAssay Description:Binding affinity to human P2Y12 expressed in astrocytoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50302669BDBM50302669((S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-5-oxo-4-(...)
Affinity DataIC50: 71nMAssay Description:Displacement of tritium-labeled 2MeSADP from human P2Y12 expressed in CHO cells measured after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594693BDBM50594693(CHEMBL5187308)
Affinity DataIC50: 100nMAssay Description:Inhibition of 2-MeS-ADP induced P2Y12 (unknown origin) signalling expressed in CHO cells membrane incubated for 45 mins by 35S-GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594692BDBM50594692(CHEMBL5190691)
Affinity DataIC50: 260nMAssay Description:Inhibition of 2-MeS-ADP induced P2Y12 (unknown origin) signalling expressed in CHO cells membrane incubated for 45 mins by 35S-GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594675BDBM50594675(CHEMBL5209548)
Affinity DataIC50: 320nMAssay Description:Binding affinity to P2Y12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594676BDBM50594676(CHEMBL5172707)
Affinity DataIC50: 379nMAssay Description:Displacement of [33P]2MeSADP from human P2Y12 expressed in CHO cell membranes preincubated for 15 mins followed by [33P]2MeSADP addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594674BDBM50594674(CHEMBL5183695)
Affinity DataIC50: 480nMAssay Description:Displacement of [3H]2MeSADP from P2Y12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594690BDBM50594690(CHEMBL5197988)
Affinity DataIC50: 1.35E+3nMAssay Description:Displacement of 2-MeS[3H]-ADP from P2Y12 (unknown origin) expressed in HEK293 cells preincubated for 5 mins followed by 2-MeS[3H]-ADP addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594673BDBM50594673(CHEMBL5177774)
Affinity DataIC50: 2.20E+3nMAssay Description:Displacement of [3H]2MeSADP from P2Y12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50233805BDBM50233805(CHEMBL4077922 | US11021454, Compound Salvianolic a...)
Affinity DataKi:  1.56E+4nMAssay Description:Displacement of [3H]2MeSADP from human P2Y12 expressed in U2OS cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 1(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414250BDBM50414250(CHEMBL457077)
Affinity DataKi:  2.03E+4nMAssay Description:Displacement of [3H]2MeSADP from human P2Y1 expressed in U2OS cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
Al-Ahliyya Amman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587725BDBM50587725(CHEMBL1615434)
Affinity DataKi:  3.64E+4nMAssay Description:Displacement of [3H]2MeSADP from human P2Y12 expressed in U2OS cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed