Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50015321
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128107(1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128110(1-[2-(4-Chloro-phenoxy)-ethyl]-4-methyl-piperidine...)
Affinity DataKi:  0.860nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585434(CHEMBL5093782)
Affinity DataKi:  0.890nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585435(CHEMBL5083713)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128108(1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585436(CHEMBL5080230)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50001028(Talwin | PENTAZOCINE (+) | Pentazocine,(+/-) | 6,1...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585431(CHEMBL5082024)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585430(CHEMBL5094446)
Affinity DataKi:  17nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585431(CHEMBL5082024)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585429(CHEMBL5087328)
Affinity DataKi:  21nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585439(CHEMBL5089619)
Affinity DataKi:  24nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50062551(Dolutegravir | GSK1349572 | CHEBI:76010 | S-349572)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585437(CHEMBL5090648)
Affinity DataKi:  36nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585438(CHEMBL5090805)
Affinity DataKi:  43nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128108(1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585439(CHEMBL5089619)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585432(CHEMBL5084203)
Affinity DataKi:  59nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585430(CHEMBL5094446)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585429(CHEMBL5087328)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585432(CHEMBL5084203)
Affinity DataKi:  116nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585434(CHEMBL5093782)
Affinity DataKi:  170nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585438(CHEMBL5090805)
Affinity DataKi:  175nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128107(1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...)
Affinity DataKi:  186nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585435(CHEMBL5083713)
Affinity DataKi:  187nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50128110(1-[2-(4-Chloro-phenoxy)-ethyl]-4-methyl-piperidine...)
Affinity DataKi:  239nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585437(CHEMBL5090648)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585440(CHEMBL5083085)
Affinity DataKi:  379nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585433(CHEMBL5082189)
Affinity DataKi:  411nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585440(CHEMBL5083085)
Affinity DataKi:  636nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585436(CHEMBL5080230)
Affinity DataKi:  723nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585441(CHEMBL5078846)
Affinity DataKi:  809nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585433(CHEMBL5082189)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585441(CHEMBL5078846)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed