Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50017083
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599647BDBM50599647(CHEMBL5189273)
Affinity DataIC50: 117nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599635BDBM50599635(CHEMBL5200414)
Affinity DataIC50: 120nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599630BDBM50599630(CHEMBL5176486)
Affinity DataIC50: 140nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599631BDBM50599631(CHEMBL5178149)
Affinity DataIC50: 150nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599633BDBM50599633(CHEMBL5201817)
Affinity DataIC50: 150nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599651BDBM50599651(CHEMBL5186395)
Affinity DataIC50: 153nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599626BDBM50599626(CHEMBL5176190)
Affinity DataIC50: 160nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 61925BDBM61925(KUC104122N | 2-(3-oxidanylidene-1,2-benzothiazol-2...)
Affinity DataIC50: 165nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599632BDBM50599632(CHEMBL5170578)
Affinity DataIC50: 180nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599629BDBM50599629(CHEMBL5188739)
Affinity DataIC50: 190nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 61902BDBM61902(KUC103649N | 2-(6-fluoranyl-3-oxidanylidene-1,2-be...)
Affinity DataIC50: 190nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599625BDBM50599625(CHEMBL5198897)
Affinity DataIC50: 190nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599639BDBM50599639(CHEMBL5191265)
Affinity DataIC50: 210nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599640BDBM50599640(CHEMBL5183334)
Affinity DataIC50: 220nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599653BDBM50599653(CHEMBL5182008)
Affinity DataIC50: 224nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599642BDBM50599642(CHEMBL5173090)
Affinity DataIC50: 230nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599638BDBM50599638(CHEMBL5204604)
Affinity DataIC50: 250nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599645BDBM50599645(CHEMBL5198660)
Affinity DataIC50: 253nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599648BDBM50599648(CHEMBL5182841)
Affinity DataIC50: 287nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599652BDBM50599652(CHEMBL5188666)
Affinity DataIC50: 287nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599634BDBM50599634(CHEMBL5177648)
Affinity DataIC50: 300nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599636BDBM50599636(CHEMBL5175672)
Affinity DataIC50: 310nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599649BDBM50599649(CHEMBL5201634)
Affinity DataIC50: 328nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599650BDBM50599650(CHEMBL5199130)
Affinity DataIC50: 334nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599637BDBM50599637(CHEMBL5177146)
Affinity DataIC50: 335nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599628BDBM50599628(CHEMBL5207227)
Affinity DataIC50: 380nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599643BDBM50599643(CHEMBL5204705)
Affinity DataIC50: 388nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599654BDBM50599654(CHEMBL5187129)
Affinity DataIC50: 393nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599627BDBM50599627(CHEMBL5172482)
Affinity DataIC50: 400nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599657BDBM50599657(CHEMBL5175153)
Affinity DataIC50: 416nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599658BDBM50599658(CHEMBL5191706)
Affinity DataIC50: 443nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 512583BDBM512583(acs.jmedchem.1c00409_ST.176)
Affinity DataIC50: 490nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599655BDBM50599655(CHEMBL5191848)
Affinity DataIC50: 524nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599646BDBM50599646(CHEMBL5198161)
Affinity DataIC50: 540nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599644BDBM50599644(CHEMBL5190812)
Affinity DataIC50: 680nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599641BDBM50599641(CHEMBL5170392)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599656BDBM50599656(CHEMBL5177329)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60593BDBM60593(6-fluoro-1,2-benzisothiazol-3(2H)-one | 6-fluorany...)
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 61902BDBM61902(KUC103649N | 2-(6-fluoranyl-3-oxidanylidene-1,2-be...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRpMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599626BDBM50599626(CHEMBL5176190)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of SARS-CoV-2 RdRpMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599659BDBM50599659(CHEMBL5187806)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599644BDBM50599644(CHEMBL5190812)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of SARS-CoV-2 RdRpMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed