Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50017602
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50328671((6aR,9R,10aR)-3-(1-hexylcyclobutyl)-6,6-dimethyl-6...)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603275(CHEMBL5187249)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603264(CHEMBL5206676)
Affinity DataKi:  0.460nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603277(CHEMBL5194920)
Affinity DataKi:  0.550nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603266(CHEMBL5203712)
Affinity DataKi:  0.550nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603279(CHEMBL5203974)
Affinity DataKi:  0.570nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603286(CHEMBL5183405)
Affinity DataKi:  0.610nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603268(CHEMBL5206273)
Affinity DataKi:  0.660nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603278(CHEMBL5176554)
Affinity DataKi:  0.690nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50328664((6aR,10aR)-3-(1-Hexyl-cyclobut-1-yl)-6,6a,7,8,10,1...)
Affinity DataKi:  0.840nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603288(CHEMBL5178005)
Affinity DataKi:  0.920nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603284(CHEMBL5178943)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603281(CHEMBL5187812)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603283(CHEMBL5191435)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603274(CHEMBL5203428)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603266(CHEMBL5203712)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at N-terminal 3HA-tagged human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50328672((6aR,9R,10aR)-3-[1-(5-Bromopentyl)cyclobutyl]-6a,7...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at N-terminal 3HA-tagged human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603280(CHEMBL5177375)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50328673((6aR,9S,10aR)-3-[1-(5-Bromopentyl)cyclobutyl]-6a,7...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603272(CHEMBL5208446)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603285(CHEMBL5170526)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603286(CHEMBL5183405)
Affinity DataEC50:  2nMAssay Description:Agonist activity at rat CB1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation measured for 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50328669((6aR,10aR)-3-[1-(5-Bromopentyl)cyclobutyl]-6,6a,7,...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603265(CHEMBL5182571)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603278(CHEMBL5176554)
Affinity DataEC50:  3.90nMAssay Description:Agonist activity at rat CB1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation measured for 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603271(CHEMBL5195537)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603276(CHEMBL5186742)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603270(CHEMBL5209282)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603266(CHEMBL5203712)
Affinity DataEC50:  7.5nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as assessed as induction of beta-arrestin 2 recruitment measured for 90 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603269(CHEMBL5176899)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603287(CHEMBL5169602)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603266(CHEMBL5203712)
Affinity DataEC50:  8.60nMAssay Description:Agonist activity at rat CB1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation measured for 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603273(CHEMBL5198520)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603267(CHEMBL5189278)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603263(CHEMBL5188390)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as assessed as induction of beta-arrestin 2 recruitment measured for 90 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603282(CHEMBL5198210)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50603262(CHEMBL5197833)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]-CP-55,940 from CB1R in rat brain membranes measured by radioligand based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed