Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50015254
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataIC50: 70nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584681(CHEMBL5074175)
Affinity DataIC50: 110nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50094569(Cyproterone 17-O-acetate | cyproterone acetate | C...)
Affinity DataIC50: 259nMAssay Description:Antagonist activity at human AR AF2 assessed as inhibition of fluorescent-labelled D11-FxxLF peptide Co-activator to receptor by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584670(CHEMBL5085066)
Affinity DataIC50: 470nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584688(CHEMBL5074767)
Affinity DataIC50: 1.55E+3nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584694(CHEMBL5077543)
Affinity DataIC50: 1.59E+3nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584689(CHEMBL5081582)
Affinity DataIC50: 1.77E+3nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584693(CHEMBL5074003)
Affinity DataIC50: 2.25E+3nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584677(CHEMBL5075240)
Affinity DataIC50: 2.27E+3nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584683(CHEMBL5090667)
Affinity DataIC50: 3.37E+3nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584680(CHEMBL5077404)
Affinity DataIC50: 4.16E+3nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584678(CHEMBL5085212)
Affinity DataIC50: 5.02E+3nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584671(CHEMBL5090685)
Affinity DataIC50: 5.73E+3nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584685(CHEMBL1463660)
Affinity DataIC50: 6.11E+3nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584695(CHEMBL5075580)
Affinity DataIC50: 7.05E+3nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584691(CHEMBL5086603)
Affinity DataIC50: 7.90E+3nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584692(CHEMBL5078718)
Affinity DataIC50: 1.15E+4nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584670(CHEMBL5085066)
Affinity DataIC50: 1.81E+4nMAssay Description:Antagonist activity at human AR AF2 assessed as inhibition of fluorescent-labelled D11-FxxLF peptide Co-activator to receptor by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataKd:  4.02E+4nMAssay Description:Binding affinity to human AR LBD (663 to 920 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant by biolayer interfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584679(CHEMBL5078897)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584696(CHEMBL5082552)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584682(CHEMBL5090120)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584684(CHEMBL5084672)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584672(CHEMBL5077660)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584687(CHEMBL5087539)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584686(CHEMBL5074318)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584674(CHEMBL5081224)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584673(CHEMBL5091772)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584676(CHEMBL5076171)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584675(CHEMBL5088542)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584690(CHEMBL5088810)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity against human androgen receptor expressed in human LNCap cells trasfected with ARR2PB-eGFP cells incubated for 3 days by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584670(CHEMBL5085066)
Affinity DataKd:  7.59E+4nMAssay Description:Binding affinity to human AR LBD (663 to 920 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant in presence of DHT ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataKd:  2.95E+5nMAssay Description:Binding affinity to human AR LBD (663 to 920 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant in presence of DHT ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584670(CHEMBL5085066)
Affinity DataKd:  7.60E+7nMAssay Description:Binding affinity to human AR LBD (663 to 920 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant by biolayer interfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed