Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50015723
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Evotec (U.K.)

Curated by ChEMBL
LigandPNGBDBM577(VX-478 | 141W94 | APV | BDBM50215393 | CHEMBL116 |...)
Affinity DataKi:  0.0800nMAssay Description:Binding affinity to HIV-1 protease assessed as inhibition constant incubated for 60 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Evotec (U.K.)

Curated by ChEMBL
LigandPNGBDBM50589183(CHEMBL5180158)
Affinity DataKi:  0.360nMAssay Description:Binding affinity to HIV-1 protease assessed as inhibition constant incubated for 60 mins by mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Evotec (U.K.)

Curated by ChEMBL
LigandPNGBDBM50589182(CHEMBL4116419)
Affinity DataIC50: 1nMAssay Description:Inhibition of BTK in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Evotec (U.K.)

Curated by ChEMBL
LigandPNGBDBM50039978(CHEMBL3352876)
Affinity DataIC50: 4nMAssay Description:Inhibition of BTK in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Evotec (U.K.)

Curated by ChEMBL
LigandPNGBDBM50505177(CHEMBL4117175)
Affinity DataIC50: 23nMAssay Description:Inhibition of BTK in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Evotec (U.K.)

Curated by ChEMBL
LigandPNGBDBM205094(US9556147, 3)
Affinity DataIC50: 24nMAssay Description:Inhibition of BTK in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)